Rare Factor Deficiencies

Table 4. HTC Population Profile Patient Characteristics, Rare Factor Deficiencies (excluding Factor VIII and Factor IX), data reported from 1/1/2012 through 03/31/2019

HTC Population Profile Patient Characteristics, Rare Factor Deficiencies (excluding Factor VIII and Factor IX)
FI FII FV Factors V &
VIII, combined
FVII FX FXI FXIII Alpha-2 Antiplasmin Deficiency PAI-1 Deficiency
# (%) #> (%) # (%) # (%) # (%) # (%) # (%) # (%) # (%) # (%)
# of patients 269 (100) 80 (100) 458 (100) 22 (100) 1930 (100) 213 (100) 1212 (100) 211 (100) 7 (100) 280 (100)
Age (years) <2 12 (4) * * 12 (3) * * 27 (1) * * 45 (4) 9 (4) * * 7 (3)
2-10 77 (29) 16 (20) 55 (12) * * 541 (28) 44 (21) 196 (16) 37 (18) * * 50 (18)
11-19 74 (28) 31 (39) 154 (34) * * 779 (40) 67 (31) 333 (27) 42 (20) * * 117 (42)
20-44 64 (24) 21 (26) 149 (33) 8 (36) 394 (20) 50 (23) 304 (25) 89 (42) * * 71 (25)
45-64 29 (11) * * 66 (14) * * 118 (6) 35 (16) 179 (15) 26 (12) * * 19 (7)
65+ 13 (5) * * 22 (5) * * 71 (4) * * 155 (13) 8 (4) * * 16 (6)
Sex Male 112 (42) 29 (36) 178 (39) 11 (50) 957 (50) 92 (43) 555 (46) 102 (48) * * 92 (33)
Female 157 (58) 51 (64) 280 (61) 11 (50) 973 (50) 121 (57) 657 (54) 109 (52) * * 188 (67)
Ethnicity Hispanic, Latino/a, or Spanish origin 30 (11) * * 67 (15) * * 433 (22) 49 (23) 157 (13) * * * * * *
Not Hispanic, Latino/a, or Spanish origin 231 (86) 53 (66) 377 (82) * * 1434 (74) 158 (74) 1031 (85) 167 (79) * * 229 (82)
Unknown 8 (3) * * 14 (3) * * 63 (3) 6 (3) 24 (2) * * * * * *
Race American Indian/Alaska Native * * * * * * * * * * * * * * * * * * * *
Asian 10 (4) * * 10 (2) * * 65 (3) 16 (8) 44 (4) 22 (10) * * * *
Black or African American 13 (5) * * 18 (4) * * 342 (18) 25 (12) 54 (4) 23 (11) * * 27 (10)
Native Hawaiian or other Pacific Islander * * * * * * * * * * * * * * * * * * * *
White 219 (81) 66 (83) 399 (87) 15 (68) 1351 (70) 151 (71) 1041 (86) 150 (71) * * 229 (82)
More than one of these * * * * * * * * 31 (2) * * 8 (1) * * * * * *
Unknown 21 (8) 7 (9) 26 (6) * * 126 (7) 20 (9) 58 (5) 13 (6) * * 11 (4)
Insurance Status Insured 260 (97) 72 (90) 445 (97) 20 (91) 1885 (98) 210 (99) 1185 (98) 208 (99) * * 263 (94)
Uninsured * * * * * * * * 26 (1) * * 10 (1) * * * * 11 (4)
Unknown * * * * * * * * 19 (1) * * 17 (1) * * * * 6 (2)
History of HCV infection Yes 8 (3) 7 (9) 10 (2) * * 19 (1) 8 (4) 25 (2) 11 (5) * * * *
No 177 (66) 49 (61) 320 (70) 14 (64) 1374 (71) 154 (72) 888 (73) 171 (81) * * 152 (54)
Unknown 84 (31) 24 (30) 128 (28) * * 537 (28) 51 (24) 299 (25) 29 (14) * * * *
History of HIV infection Yes * * * * * * * * * * * * 6 (0) * * * * * *
No 179 (67) 55 (69) 325 (71) 14 (64) 1393 (72) 164 (77) 911 (75) 182 (86) * * 151 (54)
Unknown * * * * * * * * * * * * 295 (24) * * * * * *

† The HTC Population Profile contains 44 transsexual individuals. For confidentiality purposes, the number of transsexual patients is too small to report by year or other characteristics. Transsexual patients have been included in the counts of male and female according to the sex assigned to them at birth since hemophilia and von Willebrand disease, the most common congenital bleeding disorders, affect the sexes differently.

* Counts greater than zero but less than five have been suppressed to protect patient confidentiality. Additional cells may be suppressed to prevent derivation of these counts by subtraction.