Factor VIII and Factor IX

Table 2. HTC Population Profile Patient Characteristics, Factor VIII and Factor IX, data reported from 1/1/2012 through 03/31/2019

HTC Population Profile Patient Characteristics, Factor VIII and Factor IX
Hemophilia A (Factor VIII deficiency) (n=19192) Hemophilia B (Factor IX deficiency) (n=6095)
Mild Moderate Severe Severity Unknown Mild Moderate Severe Severity Unknown
# (%) # (%) # (%) # (%) # (%) # (%) # (%) # (%)
# of patients 7095 (100) 3148 (100) 8615 (100) 334 (100) 2276 (100) 2168 (100) 1552 (100) 99 (100)
Age (years) <2 153 (2) 93 (3) 218 (3) 16 (5) 65 (3) 54 (2) 53 (3) * *
2-10 1130 (16) 590 (19) 1710 (20) 53 (16) 390 (17) 409 (19) 301 (19) 19 (19)
11-19 1571 (22) 699 (22) 1922 (22) 36 (11) 482 (21) 471 (22) 290 (19) 15 (15)
20-44 2365 (33) 1149 (36) 3682 (43) 153 (46) 743 (33) 719 (33) 621 (40) 30 (30)
45-64 1210 (17) 430 (14) 894 (10) 56 (17) 386 (17) 343 (16) 224 (14) 25 (25)
65+ 666 (9) 187 (6) 189 (2) 20 (6) 210 (9) 172 (8) 63 (4) * *
Sex Male 5280 (74) 3091 (98) 8576 (100) 140 (42) 1506 (66) 2148 (99) 1546 (100) 61 (62)
Female 1815 (26) 57 (2) 39 (0) 194 (58) 770 (34) 20 (1) 6 (0) 38 (38)
Ethnicity Hispanic, Latino/a, or Spanish origin 1343 (19) 645 (20) 1468 (17) 63 (19) 162 (7) 135 (6) 289 (19) 11 (11)
Not Hispanic, Latino/a, or Spanish origin 5630 (79) 2472 (79) 7077 (82) 253 (76) 2070 (91) 2015 (93) 1247 (80) 82 (83)
Unknown 122 (2) 31 (1) 70 (1) 18 (5) 44 (2) 18 (1) 16 (1) 6 (6)
Race American Indian/Alaska Native 108 (2) 40 (1) 68 (1) * * * * 27 (1) 11 (1) * *
Asian 182 (3) 117 (4) 434 (5) 18 (5) 35 (2) 30 (1) 80 (5) * *
Black or African American 423 (6) 427 (14) 1317 (15) 33 (10) 171 (8) 88 (4) 231 (15) 6 (6)
Native Hawaiian or other Pacific Islander 8 (0) 10 (0) 53 (1) * * * * 12 (1) 10 (1) * *
White 6047 (85) 2425 (77) 6425 (75) 245 (73) 2008 (88) 1978 (91) 1172 (76) 88 (89)
More than one of these 85 (1) 42 (1) 130 (2) * * 10 (0) 9 (0) 15 (1) * *
Unknown 242 (3) 87 (3) 188 (2) 28 (8) 47 (2) 24 (1) 33 (2) * *
Insurance Status Insured 6796 (96) 3030 (96) 8320 (97) 300 (90) 1931 (85) 1719 (79) 1507 (97) 79 (80)
Uninsured 217 (3) 88 (3) 214 (2) 22 (7) 291 (13) 432 (20) 37 (2) 12 (12)
Unknown 82 (1) 30 (1) 81 (1) 12 (4) 54 (2) 17 (1) 8 (1) 8 (8)
History of HCV infection Yes 844 (12) 660 (21) 2204 (26) 31 (9) 189 (8) 379 (17) 491 (32) 12 (12)
No 5282 (74) 2236 (71) 5857 (68) 200 (60) 1636 (72) 1506 (69) 941 (61) 56 (57)
Unknown 969 (14) 252 (8) 554 (6) 103 (31) 451 (20) 283 (13) 120 (8) 31 (31)
History of HIV infection Yes 109 (2) 184 (6) 905 (11) 13 (4) 22 (1) 45 (2) 127 (8) * *
No 5929 (84) 2685 (85) 7073 (82) 222 (66) 1785 (78) 1812 (84) 1291 (83) 65 (66)
Unknown 1057 (15) 279 (9) 637 (7) 99 (30) 469 (21) 311 (14) 134 (9) * *

† The HTC Population Profile contains 44 transsexual individuals. For confidentiality purposes, the number of transsexual patients is too small to report by year or other characteristics. Transsexual patients have been included in the counts of male and female according to the sex assigned to them at birth since hemophilia and von Willebrand disease, the most common congenital bleeding disorders, affect the sexes differently.

* Counts greater than zero but less than five have been suppressed to protect patient confidentiality. Additional cells may be suppressed to prevent derivation of these counts by subtraction.

** Counts greater than zero but less than five have been suppressed to protect patient confidentiality. Additional cells may be suppressed to prevent derivation of these counts by subtraction. Greater than 99% of these patients are male.