Newborn Screening (NBS) Data, North Carolina, 2016–2020

The Bloodline Sickle Cell Data Collection Program Quarterly Newsletter

The Bloodline is a quarterly newsletter that provides updates about the SCDC program. Click here to read past newsletters, and subscribe to the newsletter to stay updated on the SCDC program’s health communications activities, data, presentations, and more.

The Sickle Cell Data Collection (SCDC) program monitors and reports on the health of people with sickle cell disease (SCD) over time. Data from the state’s newborn screening (NBS) program are an important part of the SCDC program because they provide information about the SCD births that occur every year. North Carolina’s most recent NBS data, 2016–2020, are presented below.

The data provide the number of babies born with SCD in the state, their demographics, and their type of SCD. The people included in these data were born in North Carolina during 2016–2020 and reported by the state NBS program with a confirmed diagnosis of SCD.

The individuals in the NBS data are also included in the North Carolina SCDC program data for the years during which they were living in the state

Map 1: Number of SCD births by county of birth, North Carolina Newborn Screening Data, 2016–2020
Map 1: Number of SCD births by county of birth, North Carolina Newborn Screening Data, 2016–2020

Map 1: About 66% of the counties in North Carolina had at least one SCD birth during 2016–2020. More than 50% of the SCD births in North Carolina occurred in five counties: Mecklenburg, Wake, Guilford, Cumberland, or Durham.

Figure 1: Annual Number of SCD Births, North Carolina Newborn Screening Data, 2020
Figure 1: Annual Number of SCD Births, North Carolina Newborn Screening Data, 2020

Figure 1. There were 109 SCD births in North Carolina during 2020.

Figure 2: Sex, North Carolina Newborn Screening Data, 2016–2020
Figure 2: Sex, North Carolina Newborn Screening Data, 2016–2020

Figure 2: There were a total of 624 SCD births in North Carolina during 2016–2020. There were 313 male births (50%) and 302 female births (48%).

*NOTE: The sum of all categories may be less than the total number of births if there are individuals with missing data.

Figure 3: Confirmed Type of SCD, North Carolina Newborn Screening Data, 2016–2020
Figure 3: Confirmed Type of SCD, North Carolina Newborn Screening Data, 2016–2020

Figure 3: Forty-nine percent of the SCD births in North Carolina during 2016–2020 were babies with hemoglobin (Hb) S/S or S/β0 thalassemia, 22% were Hb S/C, and 4% were Hb S/β+ thalassemia. The remaining babies had other or unknown types of SCD.

*NOTE: The sum of all categories may not total to 100% due to rounding errors.