Multisystem Inflammatory Syndrome in Children (MIS-C)

Holding the hand of a sick child.

MIS-C and COVID-19

CDC is investigating multisystem inflammatory syndrome in children, a rare but serious complication associated with COVID-19.

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What is MIS-C?

Multisystem inflammatory syndrome in children (MIS-C) is a condition where different body parts can become inflamed, including the heart, lungs, kidneys, brain, skin, eyes, or gastrointestinal organs. Children with MIS-C may have a fever and various symptoms, including abdominal (gut) pain, vomiting, diarrhea, neck pain, rash, bloodshot eyes, or feeling extra tired. We do not yet know what causes MIS-C. However, many children with MIS-C had the virus that causes COVID-19, or had been around someone with COVID-19.

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MIS-C Emergency Care

Contact your child’s doctor, nurse, or clinic right away if your child is showing symptoms of MIS-C or symptoms of COVID-19. If your child is showing any emergency warning signs including trouble breathing, pain or pressure in the chest that does not go away, new confusion, inability to wake up or stay awake, bluish lips or face, or severe abdominal pain, call 911 or go to the emergency room.

Page last reviewed: May 29, 2020