Issue 8, February 27, 2012

Vol. 4, Issue: 8, 2/27/12

Welcome to Science Clips, CDC’s weekly digest! The report consists of four components:

We welcome Science Clips readers to a new feature consisting of periodic essays which briefly describe the week’s featured articles. Feedback on this or any aspect of Science Clips is welcome and can be sent to

Headlining this week’s selections is a Community Guide review by HB Chin et al on the effectiveness of comprehensive risk reduction and abstinence education to prevent adolescent pregnancy, HIV, and STI. The review concludes that group-based comprehensive risk reduction is effective, while no conclusions were reached regarding abstinence education. Interested readers may wish to consult the accompanying methods paper by TA Sipe et al, also listed in Clips this week. SW Sorensen and colleagues, writing in PLoS ONE, conclude based on modeled data that a comprehensive “test-and-treat” approach could “…substantially reduce HIV incidence among urban MSM…”. More effective prevention and treatment strategies may be needed for Hepatitis C, which according to KN Ly and colleagues from the CDC Division of Viral Hepatitis, now causes more deaths in the US than HIV.

Several features this week address the broad spectrum of vaccine-preventable disease surveillance, vaccine development, and implementation. MB Pearce et al document the ability of variant influenza A H3N2 virus to replicate and transmit efficiently in ferrets, highlighting the need for ongoing human virologic surveillance. The CDC-developed chimeric dengue vaccine (DENVax) is shown to be immunogenic and efficacious in a mouse model, in a paper published in Vaccine by JN Brewoo in concert with multiple CDC staff. Enhanced immunization delivery is the focus of the article in Pediatrics authored by LY Fu, writing with both CDC and non-CDC collaborators; they found that quality improvement could be sustained across multiple health centers for more than 18 months.

Other articles this week emphasize the importance of clinical and community prevention across the lifespan. The potential to identify and intervene with mothers at risk for having children with fetal alcohol syndrome is an implication of the study by MJ Cannon et al. MH Swahn et al, writing in Int J Environ Res Public Health, identify shared “modifiable risk factors” for self-harm and suicide attempts among urban adolescents. Finally, separate analyses in Am J Public Health, first authored by WW Thompson and LL Ogden, draw attention to the importance of healthy aging and the key role to be played by healthcare and public health services.

John Iskander

Editor, Science Clips

Science Clips is a service of the Stephen B. Thacker CDC Library and CDC’s Office of the Associate Director for Science.
The Science Clips is in the public domain and may be freely forwarded and reproduced without permission. The original sources and the CDC Science Clips should be cited as sources. Articles featured in Science Clips may be in-press or uncorrected proofs.

For assistance in obtaining copies of these articles, contact the library at or 404-639-1717. Please note that links below to CDC licensed materials are available only through the Intranet and may go through the SFX server. From the SFX window, just click on the full-text link to reach the full-text.

  1. Top Ten Articles of the Week

  2. CDC Authored Publications

    The names of CDC authors are indicated in bold text.

  3. Key Scientific Articles in Featured Topic Areas

  4. Public Health Articles Noted in the Media

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DISCLAIMER: Articles listed in the CDC Science Clips are selected by the Stephen B. Thacker CDC Library to provide current awareness of the public health literature. An article’s inclusion does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article’s methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.

Page last reviewed: January 31, 2019