Issue 29, July 19, 2022
CDC Science Clips: Volume 14, Issue 29, July 19, 2022
Welcome to CDC Science Clips, CDC’s weekly scientific digest.
This week, Science Clips is pleased to feature articles related to the new CDC Vital Signs on Drug Overdose Deaths Rise, Disparities Widen: Differences Grew by Race, Ethnicity, and Other Factors
Drug overdose data, reported in this week's CDC's Vital Signs, show troubling trends and widening disparities between different population groups. From 2019 to 2020, overdose death rates (number of drug overdose deaths per 100,000 people) increased 44% for Black people and 39% for American Indian and Alaska Native (AI/AN) people. Most people who died by overdose had no evidence of substance use treatment before their deaths. In fact, a lower proportion of people from racial and ethnic minority groups received treatment, compared with White people. In addition, areas with greater income inequality—a larger income gap between the rich and the poor—have higher rates of overdose deaths. Comprehensive, community-based prevention and response efforts and culturally responsive actions can address disparities in drug overdose deaths and the inequities that contribute to them.
- Increasing access to proven treatment for all people who have substance use disorder(s) is a critical part of their care and recovery.
- Harm reduction services can further reduce overdoses and save lives. Harm reduction services can include naloxone, fentanyl test strips, and referral to substance use disorder treatment. Syringe services programs can serve as a valuable way to reach people who inject drugs and provide them with overdose prevention education and opportunities to link to substance use disorder treatment.
Drug overdose death disparities are widening at the same time as a record-breaking 92,000 lives were lost to drug overdoses during 2020. More must be done to prevent overdoses and deaths.
- CDC Vital Signs
- Drug Overdose Deaths Rise, Disparities Widen
Drug overdose deaths involving cocaine and psychostimulants with abuse potential among racial and ethnic groups - United States, 2004-2019
Kariisa M, Seth P, Scholl L, Wilson N, Davis NL.
Drug Alcohol Depend. 2021 Oct 1;227:109001.
The evolving overdose epidemic: Synthetic opioids and rising stimulant-related harms
Jones CM, Bekheet F, Park JN, Alexander GC.
Epidemiol Rev. 2020 Jan 31;42(1):154-166.
The opioid crisis in black communities
James K, Jordan A.
J Law Med Ethics. 2018 Jun;46(2):404-421.
Integrating motivational interviewing and traditional practices to address alcohol and drug use among urban American Indian/Alaska Native youth
Dickerson DL, Brown RA, Johnson CL, Schweigman K, D'Amico EJ.
J Subst Abuse Treat. 2016 Jun;65:26-35.
Evaluation of increases in drug overdose mortality rates in the US by race and ethnicity before and during the COVID-19 pandemic
Friedman JR, Hansen H.
JAMA Psychiatry. 2022 Apr 1;79(4):379-381.
Buprenorphine treatment divide by race/ethnicity and payment
Lagisetty PA, Ross R, Bohnert A, Clay M, Maust DT.
JAMA Psychiatry. 2019 Sep 1;76(9):979-981.
Situating the continuum of overdose risk in the social determinants of health: A new conceptual framework
Park JN, Rouhani S, Beletsky L, Vincent L, Saloner B, Sherman SG.
Milbank Q. 2020 Sep;98(3):700-746.
Trends in and characteristics of drug overdose deaths involving illicitly manufactured fentanyls - United States, 2019-2020
O'Donnell J, Tanz LJ, Gladden RM, Davis NL, Bitting J.
MMWR Morb Mortal Wkly Rep. 2021 Dec 17;70(50):1740-1746.
Socioeconomic risk factors for fatal opioid overdoses in the United States: Findings from the Mortality Disparities in American Communities Study (MDAC)
Altekruse SF, Cosgrove CM, Altekruse WC, Jenkins RA, Blanco C.
PLoS One. 2020 ;15(1):e0227966.
Drug overdose deaths in 28 States and the District of Columbia: 2020 data from the State Unintentional Drug Overdose Reporting System (SUDORS).
Mattson CL KS, Tanz LJ, Patel P, Luo Q, Davis NL.
. SUDORS Data Brief, No 1. , 2022.
- Drug Overdose Deaths Rise, Disparities Widen
- CDC Authored Publications
The names of CDC authors are indicated in bold text.
Articles published in the past 6-8 weeks authored by CDC or ATSDR staff.
- Chronic Diseases and Conditions
Factors impacting survival in those transplanted for NASH cirrhosis: Data from the NailNASH Consortium
Rinella ME, Satapathy SK, Brandman D, Smith C, Elwir S, Xia J, Gibson M, Figueredo C, Angirekula M, Vanatta JM, Sarwar R, Jiang Y, Gregory D, Agostini T, Ko J, Podila P, Gallo G, Watt KD, Siddiqui MS.
Clin Gastroenterol Hepatol. 2022 Feb 18.
Geospatial perspectives on the intersection of chronic disease and COVID-19
Mennis J, Matthews KA, Huston SL.
Prev Chronic Dis. 2022 Jun 30;19:E39.
Assessing the impact of multicomponent interventions on colorectal cancer screening through simulation: What would it take to reach national screening targets in North Carolina?
Hicklin K, O'Leary MC, Nambiar S, Mayorga ME, Wheeler SB, Davis MM, Richardson LC, Tangka FK, Lich KH.
Prev Med. 2022 Jul 1:107126.
- Communicable Diseases
A risk measurement tool for targeted HIV prevention measures amongst young pregnant and lactating women in South Africa
Ramraj T, Abdelatif N, Chirinda W, Abdullah F, Kindra G, Goga A.
BMC Public Health. 2022 Jun 30;22(1):1277.
Magnitude and determinants of SARS-CoV-2 household transmission: a longitudinal cohort study
Daniel Kelly J, Lu S, Anglin K, Garcia-Knight M, Pineda-Ramirez J, Goldberg SA, Tassetto M, Zhang A, Donohue K, Davidson MC, Romero M, Sanchez RD, Djomaleu M, Mathur S, Chen JY, Forman CA, Servellita V, Montejano RD, Shak JR, Rutherford GW, Deeks SG, Abedi GR, Rolfes MA, Saydah S, Briggs-Hagen M, Peluso MJ, Chiu C, Midgley CM, Andino R, Martin JN.
Clin Infect Dis. 2022 Jul 5.
SARS-CoV-2 infections and reinfections among fully vaccinated and unvaccinated university athletes - 15 states, January - November 2021
Good MK, Czarnik M, Harmon KG, Aukerman D, O'Neal CS, Day C, Goerl K, Sifre K, Fink S, Riggs MA.
Clin Infect Dis. 2022 Jun 30.
Utility of a test to return strategy to identify individuals with COVID-19 in the pre-kindergarten through grade 12 school setting - District of Columbia, January 2022
Samson ME, Still WL, Mark-Carew M, Jarris DK, Idris A, van Zyl A, Addo D, Ashley P, Ike OJ, Thomas ES, Mangla AT, Nesbitt LS.
Clin Infect Dis. 2022 Jul 1.
The HIV epidemic in South Africa: Key findings from 2017 national population-based survey
Zuma K, Simbayi L, Zungu N, Moyo S, Marinda E, Jooste S, North A, Nadol P, Aynalem G, Igumbor E, Dietrich C, Sigida S, Chibi B, Makola L, Kondlo L, Porter S, Ramlagan S.
Int J Environ Res Public Health. 2022 ;19(13).
Point prevalence estimates of activity-limiting long-term symptoms among U.S. adults ≥1 month after reported SARS-CoV-2 infection, November 1, 2021
Tenforde MW, Devine OJ, Reese HE, Silk BJ, Iuliano AD, Threlkel R, Vu QM, Plumb ID, Cadwell BL, Rose C, Steele MK, Briggs-Hagen M, Ayoubkhani D, Pawelek P, Nafilyan V, Saydah SH, Bertolli J.
J Infect Dis. 2022 Jul 1.
Perinatal COVID-19 maternal and neonatal outcomes at two academic birth hospitals
Flannery DD, Zevallos Barboza A, Pfeifer MR, Hudak ML, Barnette K, Getzlaff TR, Ellington SR, Woodworth KR, Dhudasia MB, Mukhopadhyay S, Weinberg DD, Foglia EE, Puopolo KM.
J Perinatol. 2022 Jul 1:1-8.
Estimated number of COVID-19 infections, hospitalizations, and deaths prevented among vaccinated persons in the US, December 2020 to September 2021
Steele MK, Couture A, Reed C, Iuliano D, Whitaker M, Fast H, Hall AJ, MacNeil A, Cadwell B, Marks KJ, Silk BJ.
JAMA Netw Open. 2022 Jul 1;5(7):e2220385.
Interim analysis of acute hepatitis of unknown etiology in children aged <10 years - United States, October 2021-June 2022
Cates J, Baker JM, Almendares O, Kambhampati AK, Burke RM, Balachandran N, Burnett E, Potts CC, Reagan-Steiner S, Kirking HL, Sugerman D, Parashar UD, Tate JE.
MMWR Morb Mortal Wkly Rep. 2022 Jul 1;71(26):852-858.
- Disaster Preparedness and Emergency Services
Operational challenges and considerations for COVID-19 research in humanitarian settings: A qualitative study of a project in Eastern Democratic Republic of the Congo and South Sudan
Majer J, Udoh K, Beleke A, Ahmed D, Kumar D, Summers A, Ververs M, Bollemeijer I, Doocy S.
PLoS One. 2022 ;17(6):e0267822.
- Disease Reservoirs and Vectors
Predicting distributions of blacklegged ticks (Ixodes scapularis), Lyme disease spirochetes (Borrelia burgdorferi sensu stricto) and human Lyme disease cases in the eastern United States
Burtis JC, Foster E, Schwartz AM, Kugeler KJ, Maes SE, Fleshman AC, Eisen RJ.
Ticks Tick Borne Dis. 2022 Jun 30;13(5):102000.
- Environmental Health
Study of "ALS reversals": LifeTime environmental exposures (StARLiTE)
Crayle J, Lutz M, Raymond J, Mehta P, Bedlack R.
Amyotroph Lateral Scler Frontotemporal Degener. 2022 Jul 1:1-9.
- Genetics and Genomics
Effect of childhood vaccination and antibiotic use on pneumococcal populations and genome-wide associations with disease among children in Nepal: An observational study
Kandasamy R, Lo S, Gurung M, Carter MJ, Gladstone R, Lees J, Shrestha S, Thorson S, Bijukchhe S, Gautam MC, Shrestha R, Gurung S, Khadka B, McGee L, Breiman RF, Murdoch DR, Kelly DF, Shrestha S, Bentley SD, Pollard AJ.
Lancet Microbe. 2022 Jul;3(7):e503-e511.
- Health Behavior and Risk
Behaviors and attitudes of college students during an academic semester at two Wisconsin universities during the COVID-19 pandemic
Rosenblum HG, Segaloff HE, Cole D, Lee CC, Currie DW, Abedi GR, Remington PL, Kelly GP, Pitts C, Langolf K, Kahrs J, Leibold K, Westergaard RP, Hsu CH, Kirking HL, Tate JE.
J Am Coll Health. 2022 Jul 1:1-8.
Effectiveness of personal protection measures against Lyme disease: A review of epidemiologic studies from the United States
Schwartz AM, Mackeprang JM, Mead PS, Hinckley AF.
Zoonoses Public Health. 2022 Jul 5.
- Health Economics
Health economics research in primary prevention of cancer: Assessment, current challenges, and future directions
Ekwueme DU, Halpern MT, Chesson HW, Ashok M, Drope J, Hong YR, Maciosek M, Pesko MF, Kenkel DS.
J Natl Cancer Inst Monogr. 2022 Jul 5;2022(59):28-41.
The differential impact of reopening states with and without COVID-19 face mask mandates on county-level consumer spending
Dunphy C, Miller GF, Sunshine G, McCord R, Howard-Williams M, Proia K, Stephens J.
Public Health Rep. 2022 Jul 6:333549221103816.
- Health Equity and Health Disparities
US government health agencies' efforts to address HIV-related intersectional stigma
Gaist PA, Greenwood GL, Wilson A, Dempsey A, Harrison TP, Haverkate RT, Koenig LJ, McCree DH, Palmieri J, Phillips HJ.
Am J Public Health. 2022 Jun;112(S4):S401-s404.
Getting critical information during the COVID-19 pandemic: Experiences of Spanish and Chinese speakers with limited English proficiency
SteelFisher GK, Caporello HL, Lubell KM, Ben-Porath EN, Green AR, Luo F, Briseno L, Lane L, Sheff SE, Taillepierre JD, Espino L, Boyea A.
Health Secur. 2022 Jun 30.
Associations between mobility, food insecurity, and transactional sex among women in cohabitating partnerships: An analysis from 6 African countries 2016-2017
Khalifa A, Findley S, Gummerson E, Mantell JE, Hakim AJ, Philip NM, Ginindza C, Hassani AS, Hong SY, Jalloh MF, Kirungi WL, Maile L, Mgomella GS, Miller LA, Minchella P, Mutenda N, Njau P, Schwitters A, Ward J, Low A.
J Acquir Immune Defic Syndr. 2022 Aug 1;90(4):388-398.
Trends in obesity disparities during childhood
Ogden CL, Martin CB, Freedman DS, Hales CM.
Pediatrics. 2022 Jul 5.
- Healthcare Associated Infections
Antibiotic resistant infections among COVID-19 inpatients in U.S. hospitals
Baggs J, Rose AN, McCarthy NL, Wolford H, Srinivasan A, Jernigan JA, Reddy SC.
Clin Infect Dis. 2022 Jul 2.
- Immunity and Immunization
Primary care professionals' attitudes towards vaccination recommendation for patients with inflammatory bowel disease
Xu F, deJong N, Kappelman MD, Greenlund KJ, Carlson SA.
Inflamm Bowel Dis. 2022 Jul 2.
Survey of physician practices, attitudes, and knowledge regarding recombinant zoster vaccine
Hurley LP, O'Leary ST, Dooling K, Anderson TC, Crane LA, Cataldi JR, Brtnikova M, Beaty BL, Gorman C, Guo A, Lindley MC, Kempe A.
J Gen Intern Med. 2022 Jul 6.
COVID-19 vaccine uptake among patients with systemic lupus erythematosus in the American Midwest: The Lupus Midwest Network (LUMEN)
Chevet B, Figueroa-Parra G, Yang JX, Hulshizer CA, Gunderson TM, Duong SQ, Putman MS, Barbour KE, Crowson CS, Duarte-García A.
J Rheumatol. 2022 Jul 1.
COVID-19 vaccine provider availability and vaccination coverage among children aged 5-11 years - United States, November 1, 2021-April 25, 2022
DeCuir J, Meng L, Pan Y, Vogt T, Chatham-Stevens K, Meador S, Shaw L, Black CL, Harris LQ.
MMWR Morb Mortal Wkly Rep. 2022 Jul 1;71(26):847-851.
Interim recommendations of the Advisory Committee on Immunization Practices for Use of Moderna and Pfizer-BioNTech COVID-19 vaccines in children aged 6 months-5 years - United States, June 2022
Fleming-Dutra KE, Wallace M, Moulia DL, Twentyman E, Roper LE, Hall E, Link-Gelles R, Godfrey M, Woodworth KR, Anderson TC, Rubis AB, Shanley E, Jones JM, Morgan RL, Brooks O, Talbot HK, Lee GM, Bell BP, Daley M, Meyer S, Oliver SE.
MMWR Morb Mortal Wkly Rep. 2022 Jul 1;71(26):859-868.
Safety of live-attenuated vaccines in children exposed to biologic response modifiers in utero
Zerbo O, Modaressi S, Goddard K, Lewis E, Getahun D, Palmsten KK, Fuller CC, Crane B, Donahue JG, Daley MF, Jackson LA, Wodi AP, McNeil MM, Klein NP.
Pediatrics. 2022 Jul 1;150(1).
Methodology for a correlate of protection for group B Streptococcus: Report from the Bill & Melinda Gates Foundation workshop held on 10 and 11 February 2021
Gilbert PB, Isbrucker R, Andrews N, Goldblatt D, Heath PT, Izu A, Madhi SA, Moulton L, Schrag SJ, Shang N, Siber G, Sobanjo-Ter Meulen A.
Vaccine. 2022 Jun 29.
Association of caregiver attitudes with adolescent HPV vaccination in 13 southern US states
Vasudevan L, Ostermann J, Wang Y, Harrison SE, Yelverton V, Fish LJ, Williams C, Walter EB.
Vaccine X. 2022 Aug;11:100181.
Using machine learning techniques and national tuberculosis surveillance data to predict excess growth in genotyped tuberculosis clusters
Althomsons SP, Winglee K, Heilig CM, Talarico S, Silk B, Wortham J, Hill AN, Navin TR.
Am J Epidemiol. 2022 Jul 2.
Using latent class analysis to inform the design of an EHR-based national chronic disease surveillance model
Nasuti L, Andrews B, Li W, Wiltz J, Hohman KH, Patanian M.
Chronic Illn. 2022 May 3:17423953221099043.
Comparing trained and untrained probabilistic ensemble forecasts of COVID-19 cases and deaths in the United States
Ray EL, Brooks LC, Bien J, Biggerstaff M, Bosse NI, Bracher J, Cramer EY, Funk S, Gerding A, Johansson MA, Rumack A, Wang Y, Zorn M, Tibshirani RJ, Reich NG.
Int J Forecast. 2022 Jul 1.
Metamodeling for policy simulations with multivariate outcomes
Zhong H, Brandeau ML, Yazdi GE, Wang J, Nolen S, Hagan L, Thompson WW, Assoumou SA, Linas BP, Salomon JA.
Med Decis Making. 2022 Jun 23:272989x221105079.
- Injury and Violence
Motor vehicle crash deaths - United States and 28 other high-income countries, 2015 and 2019
Yellman MA, Sauber-Schatz EK.
MMWR Morb Mortal Wkly Rep. 2022 Jul 1;71(26):837-843.
The measurement of intimate partner violence using International Classification of Diseases diagnostic codes: A systematic review
Rebbe R, Adhia A, Eastman AL, Chen M, Winn J.
Trauma Violence Abuse. 2022 May 4:15248380221090977.
- Laboratory Sciences
Updated U.S. Public Health Service guideline for testing of transplant candidates aged <12 years for infection with HIV, hepatitis B virus, and hepatitis C virus - United States, 2022
Free RJ, Levi ME, Bowman JS, Bixler D, Brooks JT, Buchacz K, Moorman A, Berger J, Basavaraju SV.
MMWR Morb Mortal Wkly Rep. 2022 Jul 1;71(26):844-846.
Influenza A virus infection and pathology in nasal and periocular tissues after ocular inoculation in ferrets
Gary JM, Ritter JM, Sun X, Maines TR, Belser JA.
Vet Pathol. 2022 Jul 4:3009858221109103.
- Nutritional Sciences
Changes in spina bifida lesion level after folic acid fortification in the United States
Mai CT, Evans J, Alverson CJ, Yue X, Flood T, Arnold K, Nestoridi E, Denson L, Adisa O, Moore CA, Nance A, Zielke K, Rice S, Shan X, Dean JH, Ethen M, Hansen B, Isenburg J, Kirby RS.
J Pediatr. 2022 Jun 27.
- Occupational Safety and Health
COVID-19 test positivity by occupation using the Delphi US COVID-19 trends and impact survey, September-November 2020
Cox-Ganser JM, Henneberger PK, Weissman DN, Guthrie G, Groth CP.
Am J Ind Med. 2022 Jul 5.
Continuous NHANES survey data for environmental ambient and occupational hazard identification-feasibility and preliminary findings for osteoporosis and kidney disease
Park RM, An Y.
J Occup Environ Hyg. 2022 Jun 27:1-11.
- Parasitic Diseases
Evaluation of the residual efficacy and physical durability of five long-lasting insecticidal nets (LLINs) in Senegal
Diouf EH, Diouf M, Dieme C, Swamidoss I, Ngom EH, Senghor MW, Mbaye M, Konaté A, Coulibaly Y, Tine D, Dia I, Dotson EM, Faye O, Konaté L.
Malar J. 2022 Jul 2;21(1):210.
Identification of a rapidly-spreading triple mutant for high-level metabolic insecticide resistance in Anopheles gambiae provides a real-time molecular diagnostic for anti-malarial intervention deployment
Njoroge H, Van't Hof A, Oruni A, Pipini D, Nagi SC, Lynd A, Lucas ER, Tomlinson S, Grau-Bove X, McDermott D, Wat'senga FT, Manzambi EZ, Agossa FR, Mokuba A, Irish S, Kabula B, Mbogo C, Bargul J, Paine MJ, Weetman D, Donnelly MJ.
Mol Ecol. 2022 Jul 1.
- Public Health Leadership and Management
Living practice guidelines require robust and continuous iteration and uptake
Li T, Michaels M.
Ann Intern Med. 2022 Jul 5.
Implementation of a nationwide knowledge-based COVID-19 contact tracing training program, 2020
Ruebush E, Dennison A, Lane JT, Harper-Hardy P, Poulin A, Prather B, Wright S, Harvey D, Fraser MR.
Public Health Rep. 2022 Jul 4:333549221101327.
- Reproductive Health
Assisted reproductive technology cycles involving male factor infertility in the United States, 2017-2018: data from the National Assisted Reproductive Technology Surveillance System
Jewett A, Warner L, Kawwass JF, Mehta A, Eisenberg ML, Nangia AK, Dupree JM, Honig S, Hotaling JM, Kissin DM.
F S Rep. 2022 Jun;3(2):124-130.
Examining the ratio of obstetric beds to births, 2000-2019
DeSisto CL, Goodman DA, Brantley MD, Menard MK, Declercq E.
J Community Health. 2022 Jun 30.
- Substance Use and Abuse
Pulmonary and critical care considerations for e-cigarette, or vaping, product use-associated lung injury
Hayes D, Board A, Calfee CS, Ellington S, Pollack LA, Kathuria H, Eakin MN, Weissman DN, Callahan SJ, Esper AM, Crotty Alexander LE, Sharma NS, Meyer NJ, Smith LS, Novosad S, Evans ME, Goodman AB, Click ES, Robinson RT, Ewart G, Twentyman E.
Chest. 2022 Mar 5.
Estimated number of people who inject drugs in the United States
Bradley H, Hall E, Asher A, Furukawa N, Jones CM, Shealey J, Buchacz K, Handanagic S, Crepaz N, Rosenberg ES.
Clin Infect Dis. 2022 Jul 6.
- Zoonotic and Vectorborne Diseases
Sympatric recombination in zoonotic cryptosporidium leads to emergence of populations with modified host preference
Wang T, Guo Y, Roellig DM, Li N, Santín M, Lombard J, Kváč M, Naguib D, Zhang Z, Feng Y, Xiao L.
Mol Biol Evol. 2022 Jul 1.
Etiology of acute febrile illnesses in Southern China: Findings from a two-year sentinel surveillance project, 2017-2019
Rainey JJ, Siesel C, Guo X, Yi L, Zhang Y, Wu S, Cohen AL, Liu J, Houpt E, Fields B, Yang Z, Ke C.
PLoS One. 2022 ;17(6):e0270586.
- Chronic Diseases and Conditions
DISCLAIMER: Articles listed in the CDC Science Clips are selected by the Stephen B. Thacker CDC Library to provide current awareness of the public health literature. An article's inclusion does not necessarily represent the views of the Centers for Disease Control and Prevention nor does it imply endorsement of the article's methods or findings. CDC and DHHS assume no responsibility for the factual accuracy of the items presented. The selection, omission, or content of items does not imply any endorsement or other position taken by CDC or DHHS. Opinion, findings and conclusions expressed by the original authors of items included in the Clips, or persons quoted therein, are strictly their own and are in no way meant to represent the opinion or views of CDC or DHHS. References to publications, news sources, and non-CDC Websites are provided solely for informational purposes and do not imply endorsement by CDC or DHHS.