Mississippi Priority Topic Investments

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Mississippi Overdose Investment Snapshot

Combatting the current overdose crisis is a priority for the agency. This page provides an overview of the FY21 CDC Injury Center (NCIPC) overdose investments for the state of Mississippi.

There were 91,799 drug overdose deaths in the United States in 2020 (28.3 deaths per 100,000 standard population), a stark 30% increase from 2019. Approximately 75% of drug overdose deaths in 2020 involved an opioid, with synthetic opioids (e.g., illicitly manufactured fentanyls) accounting for more than 80% of all opioid-involved deaths. Drug overdose deaths involving synthetic opioids increased by 55% and deaths involving psychostimulants (e.g., methamphetamine) increased by 47% from 2019 to 2020. Drug overdose deaths involving cocaine also increased by 22%.

In 2020 in Mississippi there were:


overdose deaths


overdose deaths per 100,000 people (age-adjusted)

Source: NVSS – Drug Overdose Deaths

Overdose Funding At A Glance
Overdose Funding At A Glance


FY21 Mississippi Total Overdose Prevention Funding


FY21 Awards

Overdose Data to Action (OD2A)

  • Mississippi State Award: $2,307,356

Public Health and Public Safety

  • Overdose Response Strategy: $74,500*



*average award amount

Examples of How Mississippi Is Working to Prevent Overdose

overdose strategies
capacity building
Support for pregnant and parenting women

Mississippi is building a program to link pregnant and parenting women who have substance use disorder to care and services, focusing on a geographic area of high need. The program is built on a strong partnership between the Mississippi State Department of Health, Department of Mental Health, Mississippi Public Health Institute, and community partners.

capacity building
Reaching high-burden communities

Mississippi awarded six mini grants to counties disproportionately affected by opioid use disorder to conduct community-based assessments to identify gaps, available resources, and gain insight into the local perception of the drug overdose epidemic.

CDC Overdose Prevention Strategies

CDC’s Injury Center plays a critical role in addressing the drug overdose epidemic by driving progress in the five strategic priorities that guide CDC’s response framework for preventing overdoses.

Additional Resources