Kentucky Priority Topic Investments

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Kentucky Overdose Investment Snapshot

Combatting the current overdose crisis is a priority for the agency. This page provides an overview of the FY22 CDC Injury Center (NCIPC) overdose investments for the state of Kentucky.

There were 106,699 drug overdose deaths in the United States in 2021 (32.4 deaths per 100,000 standard population), a 16% increase from 2020. Approximately 75% of drug overdose deaths in 2021 involved at least one opioid; 66% of deaths involved synthetic opioids (e.g., illicitly manufactured fentanyls). Drug overdose deaths involving synthetic opioids increased 25%, deaths involving psychostimulants (e.g., methamphetamine) increased 37%, and deaths involving cocaine increased 26% from 2020 to 2021. Although deaths increased overall and in all drug categories except heroin, the increases from 2020 to 2021 were generally lower than those from 2019 to 2020, suggesting a slowing of the increase in overdose deaths.

In 2021 in Kentucky there were:


overdose deaths


overdose deaths per 100,000 people (age-adjusted)

Source: NVSS – Drug Overdose Deaths

Overdose Funding At A Glance
Overdose Funding At A Glance


FY22 Kentucky Total Overdose Prevention Funding

FY22 Awards

Overdose Data to Action (OD2A)

  • Kentucky State Award: $7,170,148

Public Health and Public Safety

  • Overdose Response Strategy: $74,500*


  • University of Kentucky: $362,500
  • University of Kentucky: $735,284

*average award amount

Examples of How Kentucky Is Working to Prevent Overdose

overdose strategies
public safety
Harm reduction education

After learning of negative interactions with law enforcement officers, Kentucky’s OD2A team worked with state harm reduction personnel and law enforcement to ensure officers understood the legality of naloxone and syringe service programs and provided supplies.

capacity building
State and local partnership

Kentucky’s State Department of Health partnered with a county health department to station a mobile harm reduction vehicle at a walk-up/drive-through COVID-19 testing location in a neighborhood with underserved medical access and care.

CDC Overdose Prevention Strategies

CDC’s Injury Center plays a critical role in addressing the drug overdose epidemic by driving progress in the five strategic priorities that guide CDC’s response framework for preventing overdoses.

  • infographic
    Strategic Priorities Overview
  • trends
    Monitor, Analyze, and Communicate Trends
  • capacity building
    Build State, Tribal, Local, and Territorial Capacity
  • healthcare
    Support Providers, Health Systems, Payors, and Employers
  • public safety
    Partner with Public Safety and Community Organizations
  • awareness
    Raise Public Awareness and Reduce Stigma

Additional Resources


1 Spencer MR, Miniño AM, Warner M. Drug overdose deaths in the United States, 2001–2021. NCHS Data Brief, no 457. Hyattsville, MD: National Center for Health Statistics. 2022. DOI: https://dx.doi. org/10.15620/cdc:122556