Compendium of Evidence-Based Interventions and Best Practices for HIV Prevention

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Compendium of Evidence-Based Interventions and Best Practices for HIV Prevention

The Compendium is a composition or collection of HIV interventions in the form of info sheets. Info sheets are categorized by Evidence-Based Interventions (EBIs) or Evidence-Informed Interventions (EIs).

Evidence-Based Interventions (EBIs)
  • Shown to have significant effects in HIV-related outcomes
  • Tested with a comparison group

EBIs work, are rigorously evaluated and provide the strongest evidence of efficacy.

Evidence-Informed Interventions (EIs)
  • Shown to have significant effects in HIV-related outcomes
  • Tested with a weaker design or fewer participants

EIs have some evidence of working and need further testing.

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Featured Interventions

The Compendium includes five chapters. For Background, Methods, or Chapter Criteria, please see consolidated PRS Compendium documentation [PDF – 2 MB]. Please select the Chapter you would like to access below.

Pre-Exposure Prophylaxis

Pre-Exposure Prophylaxis

Best practices that improve PrEP use or persistence

Structural Interventions

Structural Interventions

Best practices that use structural approaches to improve HIV outcomes

Linkage to, Retention in, and Re-engagement in HIV Care

Linkage to, Retention in, and Re-engagement in HIV Care

Best practices that improve engagement in, linkage to, retention in, or re-engagement in HIV

Medication Adherence

Medication Adherence

Interventions that improve HIV medication adherence or viral load suppression

Risk Reduction

Risk Reduction

Interventions that reduce risky sex or drug-injection behaviors

PRS Compendium Recommended Citation Format

HIV Prevention Research Synthesis Project. Compendium of Evidence-Based Interventions and Best Practices for HIV Prevention. Centers for Disease Control and Prevention. https://www.cdc.gov/hiv/research/interventionresearch/compendium/index.html. Date last updated. Date Accessed.

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