World AIDS Day 2021

December 1st is World AIDS Day, and CDC invites you to join in its observance. This year the U.S. Government’s theme, “Ending the HIV Epidemic: Equitable Access, Everyone’s Voice,” highlights our commitment to ending the HIV epidemic globally. It also highlights the importance of ensuring equitable access to quality, people-centered HIV prevention and treatment services and that the voices of all who are living with or affected by HIV are heard and valued in the AIDS response.

With support from the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR)external icon, CDC works with ministries of health; private, civil society, and faith-based organizations; and other on-the-ground partners to improve methods for finding, treating, and preventing HIV infections. CDC is helping drive progress toward HIV epidemic control using testing, treatment, and prevention services focused on populations that are disproportionately impacted by HIV.

Leadership Statement

Statement from CDC leaders on progress toward HIV epidemic control.

avatar of CDC Director Dr. Rochelle Walensky, MD, MPHavatar of CDC Director Dr. Rochelle Walensky, MD, MPH
Message from Center for Global Health Acting Director, Nathaniel Smith, MD, MPH and Division of Global HIV & TB Director, Hank Tomlinson, PhD.
In the face of remarkable progress, we have also faced unprecedented challenges, as the COVID-19 pandemic threatened to stymie progress and reverse hard-fought gains. However, CDC’s longstanding investments through PEPFAR – in laboratory science, in surveillance and health information systems, building healthcare workforce and community capacity – better prepared us to respond to COVID-19 in the countries where we work and enabled us to avoid the worst-case scenarios projected in early 2020.
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Feature Stories

Learn how CDC and partners adapted services to sustain and expand key HIV treatment and prevention activities during the COVID-19 pandemic.

Amplifying U=U Message Through Social Media
Timely diagnosis of HIV infection and sustained antiretroviral treatment (ART) increases the quality of life for a person living with HIV and prevents the spread of the virus.

Enhancing Access to Safe and Equitable HIV Services for Key Populations in Lagos
Members of key populations are most vulnerable to acquiring HIV and bear a disproportionate burden of HIV compared to the general population.

Empowering Adolescents and Young People living with HIV in Ethiopia
In 2020, about 1.75 million children and adolescents between the ages of 10 and 19 were living with HIV (C/ALHIV) worldwide (UNAIDS 2021).

Partnering to End the HIV Epidemic Worldwide

Lieutenant Commander Minesh Shah, MD, MPH of CDC Ethiopia, an internal medicine physician and a medical officer, and Dr. Jonathan Hanft of the Hennepin County Health Department discuss insights from the global and domestic HIV response efforts.

Latest Research

Latest research from CDC on global HIV and TB.

  • Forced Sexual Initiation and Early Sexual Debut and Associated Risk Factors and Health Problems Among Adolescent Girls and Young Women — Violence Against Children and Youth Surveys, Nine PEPFAR Countries, 2007–2018. Adolescent girls and young women aged 13 – 24 years, are disproportionately affected by HIV in sub-Saharan Africa resulting from biological, behavioral, and structural factors, including violence. Prevention of sexual violence and early sexual debut are vital components of CDC and PEPFAR-supported programs to control the HIV epidemic. Read more
  • Derivation and External Validation of a Risk Score for Predicting HIV-Associated Tuberculosis to Support Case Finding and Preventive Therapy Scale-Up: A Cohort Study. Among people living with HIV, more flexible and sensitive tuberculosis (TB) screening tools capable of detecting both symptomatic and subclinical active TB are needed to (1) reduce morbidity and mortality from undiagnosed TB; (2) facilitate scale-up of tuberculosis preventive therapy. Read moreexternal icon
  • Tuberculosis Treatment within Differentiated Service Delivery Models in Global HIV/TB Programming. Providing more convenient and patient-centered options for service delivery is a priority within global HIV programs. These efforts improve patient satisfaction and retention and free up time for providers to focus on new HIV diagnoses or severe illness. Read moreexternal icon
  • Risk Scores for Predicting Early Antiretroviral Therapy Mortality in sub-Saharan Africa to Inform Who Needs Intensification of Care: A Derivation and External Validation Cohort Study. Clinical scores to determine early antiretroviral therapy (ART) mortality risk have not been developed for sub-Saharan Africa, home to 70% of people living with HIV. In the absence of validated scores, WHO eligibility criteria for ART care intensification are CD4 . Read moreexternal icon

Social Media Tools

Shareable digital cards for Facebook, Twitter, and Instagram. World AIDS Day 2021 campaign hashtags include #WorldAIDSDay #WorldAIDSDay2021 and #WAD2021.

Social Media Card for download
Social Media Card for download
Social Media Card for download
Social Media Card for download

Additional Resources

More information on CDC’s global HIV & TB response can be found below.

Fact Sheets

An overview of CDC’s global efforts in response to one of the world’s greatest health threats.


Visit the PEPFAR website to learn how PEPFAR and CDC are leading efforts to control the HIV epidemic worldwide.

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PEPFAR15 Page describing how pepfar played a critical role in an effort to save millions of lives across the globe

Since its inception, CDC has played a critical role in PEPFAR’s efforts to save millions of lives across the globe.

Page last reviewed: December 1, 2021, 12:17 am