Controlling the Global HIV Epidemic

More than three decades after the first cases were reported, HIV is still a leading cause of death and a health threat to millions worldwide. The world has the tools needed to control the HIV epidemic and lay the groundwork for ending this disease. However, many people are not benefiting from the latest scientific advances. Controlling the HIV epidemic requires effective treatment and prevention programs for unreached and vulnerable populations.

As a key implementing partner of the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR), CDC works side-by-side with ministries of health, civil and faith-based organizations, private sector organizations, and other on-the-ground partners to improve methods for finding, treating, and preventing HIV. The investments made to fight HIV today will save lives and strengthen long-term economic sustainability.


December 1 is World AIDS Day. This year, the U.S. Government’s theme, Saving Lives Through American Generosity and Partnerships, highlights the highlights the transformational impact of PEPFAR, which has saved more than 16 million lives through the generosity of the American people and our partnerships with countries, communities, and many others around the world.

This is an urgent moment in the history of the HIV response. Results from the CDC-supported Population-based HIV Impact Assessments demonstrate that investments to control the HIV epidemic are working in several African countries. These survey findings also highlight that more work is needed in certain places and with certain groups. Reaching men with targeted HIV testing and treatment programs are key to controlling the HIV epidemic. As a key implementer of PEPFAR, CDC has played a leading role in helping to accelerate global progress towards controlling and eventually ending the epidemic.

Learn more about CDC’s impact in the fight against HIV, hear stories from CDC experts on the frontlines, and view shareable resources.

Key Facts

The latest statistics showing the burden of HIV and the progress made in combatting the epidemic.

Antiretroviral Treatment for
Men, Women,
and Children

PEPFAR: 14 Million

CDC: 7.3 Million

Antiretroviral Treatment to
Prevent Mother-to-child Transmission***

PEPFAR: 792,712

CDC: 450,000+

Voluntary Medical Male Circumcisions

PEPFAR: 15.2 Million

CDC: 7.5 Million

HIV-Positive Persons Screened in Care for TB***

PEPFAR: 7 Million

CDC: 4.7 Million

People Who Received a
Positive HIV Test Result***

PEPFAR: 3.3 Million

CDC: 1.8 Million


Learn more about CDC’s innovative, data-driven approach to control the HIV epidemic around the world in the videos below.

Social Media Tools

Shareable social media graphics that highlight the burden of HIV, global progress to date, and CDC’s leadership to help end the epidemic.

World AIDS Day 2018

The website describes how PEPFAR and CDC are leading efforts to accelerate controlling the HIV epidemic worldwide


The PEPFAR15 page describes how for fifteen years, CDC has played a critical role in PEPFAR’s efforts to save millions of lives across the globe.

HIV Overview

The HIV overview provides a historical look at CDC’s leadership, reach, innovation and impact in the global fight against HIV.

HIV Fact Sheet

The HIV fact sheet shows the burden of HIV worldwide and CDC’s efforts to address the epidemic.