The following six NTDs can be controlled or even eliminated through mass administration of safe and effective medicines (mass drug administration, or MDA), or other, effective interventions:

  • Dracunculiasis (Guinea Worm Disease)
  • Lymphatic Filariasis
  • Onchocerciasis
  • Schistosomiasis
  • Soil-transmitted Helminths (STH) (i.e., Ascaris, Hookworm, and Whipworm)
  • Trachoma

Controlling the vectors (e.g., mosquitoes, black flies) that transmit these diseases and improving basic water, sanitation, and hygiene are highly effective strategies against these NTDs.

Scale up of mass drug administration has been facilitated by major pharmaceutical companies including Eisai, GlaxoSmithKline, Johnson & Johnson, Merck and Co., and Pfizer, as well as support from the United States Government (led by the United States Agency of International Development, or USAID), the Bill & Melinda Gates Foundation, the Japan International Cooperation Agency, and the U.K. Department of International Development, among others.

Who is most affected?

Seven of the most common NTDs can be found in a number of countries—primarily in low- and middle-income countries of Africa, Asia, and Latin America. NTDs affect the world’s poorest people and are especially common in tropical areas, where people have little access to clean water or proper ways to dispose of human waste. Women and children who live in unsanitary environments face the biggest threat of NTDs.

Fact Sheet

Page last reviewed: March 25, 2020