Coronary Heart Disease, Family History and Public Health: From Familial Hypercholesterolemia to Elevated Lipoprotein A

April 27, 2023, 11:00 am – 12:00 noon

Heart disease remains the number one cause of death in the United States and around the world. In addition to known risk factors for heart disease, family history plays an important role. In the past decade, major advances have occurred at the intersection of genomics, heart disease and public health. Familial hypercholesterolemia (FH), a genetic disorder of cholesterol metabolism affecting millions of people, has emerged as public health genomics priority for preventing premature morbidity and mortality from heart disease. In addition, elevated lipoprotein (a) (Lp(a)) increases the risk of coronary heart disease, occur in 1 in 5 people, have a strong genetic basis, and accentuate the cardiovascular risk from FH and other risk factors.

This seminar will explore advances in FH and Lp(a) and the emerging clinical and public health approaches to reducing the burden of cardiovascular disease using genetics and family history.

Laurence Sperling
Laurence Sperling, MD, FACC, FACP, FAHA, FASPC

Katz Emory University Professor in Preventive Cardiology
Professor of Global Health
Executive Director, Million Hearts
Centers for Disease Control and Prevention (CDC) / Centers for Medicare and Medicaid Services (CMS)

Ijeoma Isiadinso
Ijeoma Isiadinso MD, MPH, FACC, FASNC

Associate Professor of Medicine
Division of Cardiology
Medical Director, Emory Center for Heart Disease Prevention

Hosted by

  • Division for Heart Disease and Stroke Prevention
  • Office of Genomics and Precision Public Health