From All of Us Research to All of Us in the Real World: Using the All of Us Research Program Data to Improve Population Health

September 29, 9:30-11:00 am, EDT

Please join this free Zoom public health genomics webinar
Registration is required

Knowledge gained from population surveys and cohort studies have dramatically advanced the prevention and treatment of diseases. Many of these studies, however, are small, lack diversity, or do not provide comprehensive risk factors and health outcome data. The All of Us Research Program is enrolling a diverse group of at least 1 million persons in the United States in order to accelerate biomedical research and improve health of individuals and populations. As of the time of this announcement, the program has already enrolled more than 500,000 participants. The program aims to make the research results accessible to participants, and it is developing new approaches to generate, access, and make data broadly available to approved researchers. All of Us opened for enrollment in May 2018 and currently enrolls participants 18 years of age or older from a network of more than 340 recruitment sites. Elements of the program protocol include health questionnaires, electronic health records (EHRs), physical measurements, the use of digital health technology, and the collection and analysis of biospecimens, including genetic analysis. Genetic data is available to researchers on more than 100,000 participants, including 165,000 with genetic array data, and 98,000 with whole genome sequencing data. The goal of the program is to have 200,000 whole genome sequencing data available to researchers by the end of 2022.

Through a Data Use Agreement with the All of Us Research Program, scientists at the Centers for Disease Control and Prevention can now register to access and analyze All of Us Research Program Data through a cloud platform. In this seminar we will: 1) Review the All of Us Research Program study design and current status, 2) Discuss its potential for providing important population data to inform implementation of disease prevention and to reduce health disparities and 3) Provide a hands-on training session for scientists interested in accessing and analyzing All of Us Data.

photo of Geoffrey S. Ginsburg


Geoffrey S. Ginsburg MD, PhD
Chief Medical and Scientific Officer, Director,
Division of Medical and Scientific Research,
All of Us Research Program, National Institutes of Health

Sheri Schully


Sheri Schully, Ph.D.
Deputy Chief Medical and Scientific Officer
Division of Medical and Scientific Research,
All of Us Research Program, National Institutes of Health

Kelsey Mayo


Kelsey Mayo, Ph.D.
Manager, Portfolio and Product Management at Vanderbilt University Medical Center
Vanderbilt University Medical Center

Selected References

  1. The NIH All of Us Research Program. All of Us Research Program | National Institutes of Health (NIH)
  2. All of Us: Release of Nearly 100,000 Whole Genome Sequences Sets Stage for New Discoveries
    J Denny et al, NIH Blog, March 2022
  3. Progress With the All of Us Research Program: Opening Access for Researchers.
    Ramirez Andrea H, et al. JAMA 2021 0 0. (24) 2441-2442
  4. Assessment of the All of Us research program’s informed consent process.
    Doerr Megan, et al. AJOB empirical bioethics 2020 0 0. (2) 72-83
  5. The “All of Us” Research Program. All of Us Research Program Investigators. N Engl J Med. 2019 Aug 15;381(7):668-676
  6. From Precision Medicine to Precision Public Health: The Dialogue Continues, Khoury MJ and Denny J, CDC Blog Post, January 2022

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Page last reviewed: July 5, 2022