Twenty-Five Years of Public Health Genomics: A Mini Symposium
February 9, 2023, 12:00 pm – 2:00 pm ET
Please join this free Zoom mini symposium
In 1997, in response to the Human Genome Project, the CDC formed the Office of Genetics and Disease Prevention, now called the Office of Genomics and Precision Public Health (OGPPH). The office serves CDC programs, other federal agencies, state health departments, and other external partners by identifying, evaluating, and implementing evidence-based genomics applications to prevent and control the country’s leading chronic, infectious, environmental, and occupational diseases.
At the same time, similar initiatives were launched around the world, culminating in an international meeting in 2005. Public health genomics was defined as the “responsible and effective translation of genome-based knowledge and technologies for the benefit of population health”.
In this mini symposium, we reflect on 25 years of progress in public health genomics around the world, review past and current achievements in the field, discuss the role of public health programs in translating advances in genomics into population health benefits, discuss workforce development and training needs, and consider ethical, legal and social issues in ensuring equitable applications of genomics into population- based research and health practice.
Ron Zimmern, MD
Chairman, PHG Foundation
Wylie Burke, MD, PhD
Professor Emeritus and Former Chair
Department of Bioethics and Humanities
University of Washington
Bartha Knoppers, PhD
Professor, Canada Research Chair in Law and Medicine,
Director of the Centre of Genomics and Policy,
Faculty of Medicine, McGill University
Debra Duquette MS
Associate Professor of Medicine
Feinberg School of Medicine,
- Khoury MJ, CDC Blog Post: Public Health Genomics at the Centers for Disease Control and Prevention: Happy 25th Anniversary!
- The impact of genomics on public health practice: the case for change.
Zimmern RL, Khoury MJ. Public Health Genomics. 2012;15(3-4):118-2
- Extending the reach of public health genomics: what should be the agenda for public health in an era of genome-based and “personalized” medicine?
Burke W, et al. Genet Med. 2010 Dec;12(12):785-91
- The path from genome-based research to population health: development of an international public health genomics network.
Burke W, et al. Genet Med. 2006 Jul;8(7):451-8.
- Ensuring the appropriate use of genetic tests.
Burke W, Zimmern RL. Nat Rev Genet. 2004 Dec;5(12):955-9.
- Communicating Precision Medicine Research: Multidisciplinary Teams and Diverse Communities.
Beans JA, et al. Public Health Genomics. 2022 Aug 23:1-9.
- 2021 McKusick Leadership Award: Learning from communities.
Burke W. Am J Hum Genet. 2022 Mar 3;109(3):390-392.
- Utility and Diversity: Challenges for Genomic Medicine.
Burke W. Annu Rev Genomics Hum Genet. 2021 Aug 31;22:1-24.
- Exome/Genome-Wide Testing in Newborn Screening: A Proportionate Path Forward.
Rahimzadeh V, et al. Front Genet. 2022 Jul 4;13:865400.
- GA4GH: International policies and standards for data sharing across genomic research and healthcare.
Rehm HL, et al. Cell Genom. 2021 Nov 10;1(2):100029.
- Return of individual research results from genomic research: A systematic review of stakeholder perspectives.
Vears DF, et al. PLoS One. 2021 Nov 8;16(11):e0258646.
- Three decades of genetic privacy: a metaphoric journey.
Knoppers BM, Beauvais MJS. Hum Mol Genet. 2021 Oct 1;30(R2):R156-R160.
- Toward better governance of human genomic data.
O’Doherty KC, et al. Nat Genet. 2021 Jan;53(1):2-8.
- Utilizing Public Health Frameworks and Partnerships to Ensure Equity in DNA-Based Population Screening.
Azriel E, et al. Front Genet. 2022 May 13;13:886755
- CDC Grand Rounds: Family History and Genomics as Tools for Cancer Prevention and Control.
Rodriguez JL, rt al. MMWR Morb Mortal Wkly Rep. 2016 Nov 25;65(46):1291-1294.
- Public Health Approaches and Barriers to Educating Providers about Hereditary Breast and Ovarian Cancer Syndrome.
Trepanier AM, et al. Healthcare (Basel). 2016 Mar 11;4(1):19.
- Strategies, actions, and outcomes of pilot state programs in public health genomics, 2003-2008.
St Pierre J, et al. Prev Chronic Dis. 2014 Jun 12;11:E97.
- Office of Genomics and Precision Public Health, Office of Science
- Precision Public Health Network