Flu Vaccination by Jet Injector
Questions & Answers
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- What is a jet injector and how is it used for vaccination?
- What flu vaccines are available via jet injector this season?
- Who can be vaccinated with flu vaccine administered by jet injector?
- How effective is flu vaccine administered by jet injector?
- What side effects are associated with flu vaccination administered via jet injection?
- Does flu vaccine administered by jet injector contain thimerosal?
A jet injector is a medical device used for vaccination that uses a high-pressure, narrow stream of fluid to penetrate the skin instead of a hypodermic needle. Jet injectors may be powered by compressed gas or springs. The devices were invented in the 1960s and were used successfully in mass vaccination efforts to eradicate smallpox and other diseases. In the past, the devices were often used to vaccinate servicemen in the armed forces.
Two flu vaccines, AFLURIA® and AFLURIA Quadrivalent®, are approved for use with a jet injector this season. AFLURIA®, is a trivalent (i.e., three strain) influenza vaccine. It provides protection against an influenza A (H1N1) virus, an influenza A (H3N2) virus and one influenza B virus. AFLURIA Quadrivalent® (i.e. four strain) influenza vaccine provides protection against an influenza A (H1N1) virus, and influenza A (h3N2) virus and two influenza B viruses. For more information, see What You Should Know for the 2017-18 Season.
Flu vaccination with AFLURIA® and AFLURIA Quadrivalent® via jet injector is approved for use in people 18 through 64 years of age.
Clinical trial data used in FDA’s approval of the jet injector flu vaccine (i.e., the PharmaJet Stratis Needle-Free Injector used with AFLURIA®) demonstrated that vaccination using this jet injector method provided a non-inferior (i.e., similar) level of immune protection compared to the same flu vaccine administered via traditional flu shot.
In adults 18 through 64 years of age, the most common injection-site adverse reactions observed in a clinical study of the jet injector flu vaccine up to 7 days post-vaccination were tenderness, swelling, pain, redness, itching and bruising. The most common systemic adverse events within this period were myalgia (muscle pain), malaise (i.e., the feeling of discomfort or unease like when you are first getting sick), and headache.
Yes. The formulations of AFLURIA®and Afluria Quadrivalent® used for administration by jet injector are from multi-dose vials, which contain thimerosal. For more information, see Thimerosal Flu Vaccines.
- FDA Approves Use of AFLURIA® Influenza Vaccine with PharmaJet’s Needle-Free Injector
- Recommendations on the control and prevention of influenza for the 2017-2018 Influenza Season
- Page last reviewed: October 12, 2017
- Page last updated: October 12, 2017
- Content source:
- Centers for Disease Control and Prevention, National Center for Immunization and Respiratory Diseases (NCIRD)
- Page maintained by: Office of the Associate Director for Communication, Digital Media Branch, Division of Public Affairs