What’s New?
June 6, 2022
Updated Ethylene Oxide Hemoglobin Adduct Data Tables Published
CDC has published updated tables for Ethylene Oxide Hemoglobin Adduct (NHANES variable name: ETHOX) in the National Report on Human Exposure to Environmental Chemicals following their temporary withdrawal on April 5, 2022.
The updated tables reflect the National Center for Health Statistics’ (NCHS) re-release of Ethylene Oxide Hemoglobin Adduct data files following correction of a calibrator bias in the ETHOX measurement impacting National Health and Nutrition Examination Survey (NHANES) cycles 2013-14 and 2015-16.
The updated tables and their associated NHANES cycles are:
Analysis of Whole Blood, Serum, and Urine Samples, NHANES 1999-2018
Ethylene Oxide Hemoglobin Adduct in Non-smokers (2013 – 2016)
Ethylene Oxide Hemoglobin Adduct in Smokers (2013 – 2016)
Ethylene Oxide Hemoglobin Adduct in Non-smokers (2013 - 2016)
CAS Number 75-21-8
Geometric mean and selected percentiles of hemoglobin adduct concentrations of (in pmol/g hemoglobin) for the non-smoking^ U.S. population from the National Health and Nutrition Examination Survey.
Download this table in PDF format [PDF 30KB]
| Demographic (Categories) | Survey (Years) |
Geometric Mean (95% CI) |
50th Percentile (95% CI) |
75th Percentile (95% CI) |
90th Percentile (95% CI) |
95th Percentile (95% CI) |
Sample Size |
|---|---|---|---|---|---|---|---|
| Total population | 13-14 | 28.5 (27.0-30.1) | 29.1 (27.6-30.5) | 37.5 (35.4-39.7) | 50.1 (46.8-52.9) | 60.8 (55.9-69.7) | 1945 |
| Total population | 15-16 | 27.7 (26.1-29.5) | 26.5 (25.2-27.7) | 34.7 (32.7-36.6) | 47.8 (44.0-53.4) | 63.8 (54.0-80.1) | 1896 |
| Age 6-11 years | 13-14 | 33.9 (31.6-36.4) | 33.2 (30.2-36.8) | 42.9 (37.9-47.9) | 52.6 (48.8-56.2) | 62.9 (55.8-76.1) | 321 |
| Age 6-11 years | 15-16 | 33.1 (31.8-34.4) | 32.2 (30.7-33.7) | 39.9 (37.8-42.0) | 52.0 (46.6-58.6) | 60.3 (56.0-64.2) | 301 |
| Age 12-19 years | 13-14 | 29.3 (27.4-31.2) | 29.6 (27.4-31.2) | 36.4 (34.4-40.0) | 49.0 (44.1-56.8) | 60.3 (48.0-79.8) | 358 |
| Age 12-19 years | 15-16 | 27.6 (25.1-30.3) | 27.0 (25.2-29.3) | 35.3 (31.3-39.1) | 46.3 (40.7-53.9) | 54.0 (46.3-60.4) | 328 |
| Age 20+ years | 13-14 | 27.8 (26.2-29.5) | 28.6 (26.9-30.1) | 36.8 (34.6-38.8) | 49.2 (44.5-54.1) | 60.8 (54.1-69.7) | 1266 |
| Age 20+ years | 15-16 | 27.2 (25.5-29.0) | 25.7 (24.1-27.2) | 33.7 (32.0-36.2) | 47.5 (43.1-54.0) | 65.8 (54.0-82.7) | 1267 |
| Males | 13-14 | 29.0 (27.2-31.0) | 30.2 (28.3-31.3) | 38.4 (35.9-40.4) | 50.5 (45.3-52.9) | 60.4 (52.9-71.1) | 897 |
| Males | 15-16 | 29.1 (27.5-30.8) | 27.3 (25.7-28.7) | 36.4 (34.4-37.8) | 51.2 (45.8-56.9) | 80.1 (60.5-83.0) | 882 |
| Females | 13-14 | 28.1 (26.5-29.8) | 28.6 (26.9-29.7) | 36.6 (34.9-38.6) | 49.6 (45.7-55.6) | 60.8 (54.7-69.7) | 1048 |
| Females | 15-16 | 26.6 (24.7-28.6) | 25.8 (24.1-27.3) | 33.2 (31.7-35.6) | 46.6 (40.5-52.6) | 56.9 (49.0-68.1) | 1014 |
| Non-Hispanic blacks | 13-14 | 31.3 (29.1-33.7) | 30.8 (28.7-33.7) | 43.9 (38.0-47.9) | 58.3 (51.7-69.2) | 78.4 (61.9-109) | 376 |
| Non-Hispanic blacks | 15-16 | 31.8 (30.1-33.6) | 30.7 (28.0-33.6) | 40.6 (38.0-44.4) | 53.9 (47.6-63.7) | 65.6 (55.2-79.2) | 340 |
| Non-Hispanic whites | 13-14 | 27.2 (25.0-29.5) | 28.1 (26.2-30.2) | 35.9 (32.6-39.1) | 48.0 (42.1-52.9) | 59.2 (49.6-69.7) | 680 |
| Non-Hispanic whites | 15-16 | 26.1 (24.0-28.4) | 25.0 (23.6-26.6) | 32.2 (29.7-34.3) | 43.1 (39.9-48.9) | 63.8 (46.4-83.1) | 569 |
| All Hispanics | 13-14 | 30.2 (28.9-31.6) | 30.0 (29.2-31.3) | 37.2 (35.1-39.5) | 49.1 (44.4-53.7) | 59.2 (52.6-73.1) | 585 |
| All Hispanics | 15-16 | 29.0 (27.7-30.4) | 27.6 (26.4-29.4) | 35.7 (34.1-37.4) | 47.4 (42.0-58.3) | 62.7 (49.4-95.4) | 654 |
Ethylene Oxide Hemoglobin Adduct in Smokers (2013 - 2016)
CAS Number 75-21-8
Geometric mean and selected percentiles of hemoglobin adduct concentrations (in pmol/g hemoglobin) for the cigarette smoking population* from the National Health and Nutrition Examination Survey.
Download this table in PDF format [PDF 21KB]
| Demographic (Categories) | Survey (Years) |
Geometric Mean (95% CI) |
50th Percentile (95% CI) |
75th Percentile (95% CI) |
90th Percentile (95% CI) |
95th Percentile (95% CI) |
Sample Size |
|---|---|---|---|---|---|---|---|
| Total population | 13-14 | 199 (177-224) | 227 (208-244) | 354 (325-391) | 526 (464-612) | 676 (610-894) | 416 |
| Total population | 15-16 | 192 (160-230) | 228 (191-258) | 374 (308-419) | 533 (458-585) | 675 (577-800) | 377 |
| Age 18-49 years | 13-14 | 197 (175-221) | 215 (177-250) | 354 (314-399) | 535 (439-649) | 725 (535-926) | 271 |
| Age 18-49 years | 15-16 | 151 (113-202) | 180 (135-243) | 296 (246-387) | 464 (341-585) | 585 (446-754) | 220 |
| Age 50+ years | 13-14 | 204 (155-268) | 243 (183-306) | 345 (304-438) | 510 (438-675) | 657 (447-1250) | 145 |
| Age 50+ years | 15-16 | 290 (245-342) | 300 (228-381) | 444 (375-565) | 606 (513-806) | 806 (577-1530) | 157 |
| Males | 13-14 | 200 (174-229) | 214 (182-250) | 383 (307-438) | 578 (435-747) | 742 (578-1060) | 231 |
| Males | 15-16 | 176 (133-234) | 227 (175-272) | 360 (294-446) | 540 (452-604) | 606 (569-685) | 231 |
| Females | 13-14 | 199 (159-248) | 230 (185-264) | 335 (290-388) | 503 (404-649) | 651 (490-926) | 185 |
| Females | 15-16 | 214 (179-256) | 228 (173-266) | 383 (296-432) | 531 (392-922) | 763 (434-1530) | 146 |
Page last reviewed: June 6, 2022
Content source: Centers for Disease Control and Prevention