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Reduction of Seizure Hospitalization Risk Among Commercially Insured Children Vaccinated Against Rotavirus — United States, 2006 – 2014

  • Rotavirus commonly causes diarrhea but can also cause seizures.  Following rotavirus vaccine introduction in the United States in 2006, the burden of rotavirus-associated diarrhea substantially declined.
  • We used U.S. insurance claims data to estimate the risk of seizure-associated hospitalization in rotavirus-vaccinated as compared to unvaccinated children under 5. We found that rotavirus vaccination significantly reduced long-term seizure hospitalization risk by 26% as compared to unvaccinated children.
  • This result is consistent with findings from prior research that followed children up to only one year following rotavirus vaccination, and supports continued universal rotavirus vaccination in the U.S.

Quote from the Disease Detective

“Rotavirus vaccination may reduce seizure hospitalization risk by up to 26% in children under 5. Reduction in seizure hospitalization risk may be an added benefit of rotavirus vaccination, supporting continued universal rotavirus vaccination in the U.S.”

-Rachel Burke, PhD, MPH, EIS Class of 2016

View abstract

Rachel Burke, PhD, MPH, EIS Class of 2016, in front of CDC’s Emergency Operations

Rachel Burke, PhD, MPH, EIS Class of 2016, in front of CDC’s Emergency Operations

Contact Information

CDC Media Relations
(404) 639-3286
media@cdc.gov

Conference Information

Spokesperson

Rachel Burke, PhD, MPH, EIS Class of 2016

 

Rachel Burke, PhD, MPH, EIS Class of 2016
CDC’s National Center for Immunization and Respiratory Diseases

Education: PhD: Emory University, Present MPH: Emory University, 2012 AB: Harvard University, 2006

Work Experience: Freelance Editor, Atlanta, GA, 2014-Present; Emory University, Atlanta, GA: Teaching Assistant, 2014; Assistant Study Coordinator, 2014-2014; Research Assistant 2013-2014; Teaching Assistant, 2013-2014; Teaching Assistant 2013-2013; Rotavirus TL, 2011-2012; Teaching Assistant, 2011-2011; Graduate Research Assistant, 2010-2011; Visiting Researcher, Instituto de Biologia Molecular Boliviano (IBMB), 2011-2011; Research Assistant, HlthMPowers, Norcross, GA, 2013-2014; Consult, Monitor Group (Deloitte)

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