Investigation Details

Posted October 28, 2022

This outbreak is over. Learn what you can do to protect yourself from getting sick from E. coli.

October 28, 2022

CDC, public health and regulatory officials in several states, and the U.S. Department of Agriculture’s Food Safety and Inspection Service (USDA-FSIS) investigated a multistate outbreak of E. coli O157:H7 infections.

Epidemiologic and traceback data showed that ground beef sold in some HelloFresh meal kits made people sick.

As of October 28, 2022, this outbreak is over.

Epidemiologic and Traceback Data

A total of seven people infected with the outbreak strain of E. coli O157:H7 were reported from six states (see map). Illnesses started on dates ranging from June 8, 2022, to August 17, 2022 (see timeline).

Sick people ranged in age from 17 to 69 years, with a median age of 25, and 43% were female. Six people were hospitalized and none developed hemolytic uremic syndrome, a serious condition that can cause kidney failure. No deaths were reported.

The true number of sick people in this outbreak is likely much higher than the number reported, and this outbreak may not have been limited to the states with known illnesses. This is because many people recover without medical care and are not tested for E. coli.

State and local public health officials interviewed people about the foods they ate in the week before they got sick. Of the six people interviewed, all six (100%) reported eating ground beef from HelloFresh meal kits.

Traceback conducted by USDA-FSIS identified that multiple sick people received ground beef in HelloFresh meal kits that was produced at establishment M46841.

Laboratory Data

Public health investigators used the PulseNet system to identify illnesses that were part of this outbreak. CDC PulseNet manages a national database of DNA fingerprints of bacteria that cause foodborne illnesses. DNA fingerprinting is performed on bacteria using a method called whole genome sequencing (WGS).

WGS showed that bacteria from sick people’s samples were closely related genetically. This suggests that people in this outbreak got sick from the same food.

WGS analysis of bacteria from seven people’s samples did not predict resistance to any antibiotics. Standard antimicrobial resistance testing by CDC’s National Antimicrobial Resistance Monitoring System (NARMS) laboratory is currently underway. These findings do not affect treatment guidance since antibiotics are not recommended for patients with E. coli O157:H7 infections.

Public Health Actions

CDC is advising people to check their freezer if they froze any of the ground beef in HelloFresh meal kits shipped from July 2 to July 21, 2022. Do not eat the ground beef if it has “EST.46841” inside the USDA inspection mark and “EST#46841 L1 22 155” or “EST#46841 L5 22 155” on the side of the packaging.

Previous Updates

CDC, public health and regulatory officials in several states, and the U.S. Department of Agriculture’s Food Safety and Inspection Service (USDA-FSIS) are collecting different types of data to investigate a multistate outbreak of E. coli O157:H7 infections.

Epidemiologic and traceback data show that some ground beef sold in HelloFresh meal kits sent directly to consumers may be contaminated with E. coli O157:H7 and have made people sick.

Epidemiologic Data

As of September 12, 2022, seven people infected with the outbreak strain of E. coli O157:H7 have been reported from six states (see map). Illnesses started on dates ranging from June 8, 2022, to August 17, 2022 (see timeline).

Sick people range in age from 17 to 69 years, with a median age of 25 years, and 57% are male. Of seven people with information available, six have been hospitalized and none developed hemolytic uremic syndrome, a serious condition that can cause kidney failure. No deaths have been reported.

The true number of sick people in an outbreak is likely higher than the number reported, and the outbreak may not be limited to the states with known illnesses. This is because many people recover without medical care and are not tested for E. coli. In addition, recent illnesses may not yet be reported as it usually takes 3 to 4 weeks to determine if a sick person is part of an outbreak.

State and local public health officials are interviewing people about the foods they ate in the week before they got sick. Of the six people interviewed, all six (100%) reported eating ground beef from meal kits received from HelloFresh.

Laboratory and Traceback Data

Public health investigators are using the PulseNet system to identify illnesses that may be part of this outbreak. CDC PulseNet manages a national database of DNA fingerprints of bacteria that cause foodborne illnesses. DNA fingerprinting is performed on bacteria using a method called whole genome sequencing (WGS). WGS showed that bacteria from sick people’s samples are closely related genetically. This means that people in this outbreak likely got sick from the same food.

Traceback conducted by USDA-FSIS identified that multiple sick people received ground beef in HelloFresh meal kits that was produced at establishment M46841. The USDA-FSIS traceback of materials used to produce the ground beef is ongoing.

Public Health Actions

CDC is advising people to check their freezer if they froze any of the ground beef in HelloFresh meal kits shipped from July 2 to July 21, 2022. Do not eat it if it has “EST.46841” inside the USDA inspection mark and “EST#46841 L1 22 155” or “EST#46841 L5 22 155” on the side of the packaging. Investigators are working to determine if additional ground beef products may be contaminated.