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Questions and Answers

What is the value of the AR Isolate Bank?

The purpose of this bacterial bank is to provide panels of resistant bacteria that can be used to challenge diagnostic devices and new antibiotic agents. The use of the AR Isolate Bank panels will support biotech and diagnostic efforts in researching, designing, and testing clinical assays or newer antimicrobial agents, and will be a valuable resource for manufacturers conducting studies in support of regulatory submissions to FDA. This in turn will support earlier diagnoses and more effective treatment options that can slow antibiotic resistance.

Where and how are isolates stored?

The isolates are stored at -70 degrees Celsius in a restricted-access facility in Atlanta, GA. Shipping and handling is also executed with safety and professionalism.

Can anyone have access to the isolates?

No. Isolates will only be provided to recognized institutions with confirmed biosafety officers. Each request for isolates will be reviewed by the CDC Isolate Bank custodians.

How can my institution have access to the isolates?

Requests for isolates are reviewed by the CDC isolate bank custodians. Approved requesters are required to provide a FedEx number for shipping. Learn how to request isolates by visiting the Requesting Isolates page .

Which data are available?

Pathogens include information on storage and propagation procedures, biosafety information, MIC results and interpretation, and known resistance mechanisms.  If isolates have been sequenced, the accession link is provided.

Are all isolates sequenced?

No. Isolate sequencing will be added over time.

Can I order single isolates?

You can only order entire panels through the website.  If you have a request for a single isolate or special order request, please contact us at ARbank@cdc.gov.

What is the cost for the isolates?

There is no cost for the isolate panels, however we do ask that the requestor pay shipping.  Upon receiving your request, a representative will contact you to confirm your order and request a FedEx number for shipping.

What is the estimated shipping cost?

For 1 to 2 collections, the shipment weight is ~15-20 lbs (due to dry ice in the shipping container) and they should consult FedEx or other appropriate shipping company for the shipping cost of this weight from CDC’s zip code of 30329 to the final destination zip code.

How soon should I expect to receive communication after submitting an order via the website?

You will receive a confirmation email within one working day of submitting your order request.  Once we have all the requested information from you, we will ship the isolate.  Please note that our shipping days are Monday-Wednesday (excluding holidays).  If you have not received a confirmation email, please contact us at ARbank@cdc.gov.

Are there additional Federal resources for isolates?

Within the U.S. Military Health System, the Walter Reed Army Institute of Research (WRAIR) maintains a collection of well-characterized resistant isolates collected from participating military hospitals through its Multidrug-resistant Organism Repository and Surveillance Network (MRSN). More information and contact information can be found on the MRSN website.

The Antibacterial Resistance Leadership Group (ARLG) maintains a Virtual Biorepository that provides investigators with access to clinically well-characterized Gram-positive and Gram- negative bacteria for the development of diagnostic tests, novel antimicrobial compounds and for studies evaluating mechanisms of resistance.  More information can be found on the ARLG’s website under Virtual Biorepository.

Don’t see the answer you need here? Submit your questions to ARbank@cdc.gov. or call 404-639-2180

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