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Methods and Limitations


We estimated the number of emergency department (ED) visits with hyperglycemic crisis (including diabetic ketoacidosis and hyperglycemic hyperosmolar state) as first-listed diagnosis using data from the National Emergency Department Sample (NEDS) of the Agency for Healthcare Research and Quality. The NEDS is a nationally representative sample of US community hospital-based EDs and the largest all-payer ED database in the United States, containing ~25-30 million records annually. The NEDS collects information on geographic, hospital, and patient characteristics as well as the nature of visits derived from State Emergency Department Databases for those “treat and release” ED visits and from State Inpatient Databases for cases admitted to hospitals from EDs. Detailed description on the data is available at [PDF–221KB] 1.

ED visits with hyperglycemic crisis as first-listed diagnosis were identified using ICD-9-CM code 250.1x-250.2x. ED visit rates among adults aged 18 years or older were calculated using two population denominators: estimates of the diabetic adult population from the National Health Interview Survey (, and estimates of the general adult population from the Census. Rates were age-adjusted on the basis of the 2000 U.S. Standard Population using age groups 18–44 years, 45–64 years, 65–74 years, and 75 years or older. For persons younger than 18 years, we reported the number of ED visits but not ED visit rates due to the lack of diabetes prevalence estimates for this population.


Because NEDS samples ED visits instead of individual persons, ED visit rates may not necessarily reflect rates per person; that is, persons who had ED visits more than once in a year may be counted more than once. No information on patient’s race/ethnicity, type of diabetes, and insulin usage is available from NEDS.



  1. Agency for Healthcare Research and Quality. Healthcare Cost and Utilization Project. Introduction to the HCUP Nationwide Emergency Department Sample (NEDS) 2009. Available at [PDF–221KB].
  2. CDC. National Center for Health Statistics. National Health Interview Survey. Available at

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