Cities Readiness Initiative

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CDC’s Cities Readiness Initiative (CRI) is a federally funded program designed to enhance preparedness in the nation’s largest population centers, where nearly 60% of the population resides, to effectively respond to large public health emergencies needing life-saving medicines and medical supplies. State and large metropolitan public health departments use CRI funding to develop, test, and maintain plans to quickly receive medical countermeasures from the Strategic National Stockpile and distribute them to local communities. The Strategic National Stockpile is the nation’s largest supply of medical countermeasures for use in a public health emergency severe enough to cause local supplies are depleted.

Participating Cities and Metropolitan Areas

The CRI project began in 2004 with 21 cities and has expanded to include a total of 72 cities and metropolitan statistical areas (MSAs) with at least one CRI city in every state.

CRI Cities and Metropolitan Areas

Albany, NY

Albuquerque, NM

Anchorage, AK

Atlanta, GA

Baltimore, MD

Baton Rouge, LA

Billings, MT

Birmingham, AL

Boise, ID

Boston, MA

Buffalo, NY

Burlington, VT

Charleston, WV

Charlotte, NC

Cheyenne, WY

Chicago, IL

Cincinnati, OH

Cleveland, OH

Columbia, SC

Columbus, OH

Dallas, TX

Denver, CO

Des Moines, IA

Detroit, MI

District of Columbia

Dover, DE

Fargo, ND

Fresno, CA

Hartford, CT

Honolulu, HI

Houston, TX

Indianapolis, IN

Jackson, MS

Kansas City, MO

Las Vegas, NV

Little Rock, AR

Los Angeles, CA

Louisville, KY

Manchester, NH

Memphis, TN

Miami, FL

Milwaukee, WI

Minneapolis, MN

Nashville, TN

New Haven, CT

New Orleans, LA

New York City, NY

Oklahoma City, OK

Omaha, NE

Orlando, FL

Peoria, IL

Philadelphia, PA

Phoenix, AZ

Pittsburgh, PA

Portland, ME

Portland, OR

Providence, RI

Richmond, VA

Riverside, CA

Sacramento, CA

Salt Lake City, UT

San Antonio, TX

San Diego, CA

San Francisco, CA

San Jose, CA

Seattle, WA

Sioux Falls, SD

St. Louis, MO

Tampa, FL

Trenton, NJ

Virginia Beach, VA

Wichita, KS


CRI is funded through CDC’s PHEP cooperative agreement. Funds are provided to the states for further distribution to the local level and to four large metropolitan areas: Chicago, Los Angeles County, New York City, and Washington, D.C., in support of all-hazards medical countermeasure distribution and dispensing planning and preparedness.

Technical Assistance to Ensure MCM Operational Readiness

CDC’s Division of State and Local Readiness (DSLR), provides technical assistance to the participating CRI jurisdictions for developing plans and testing their capability to receive, distribute, and dispense medical countermeasures. To ensure continued readiness, CDC conducts operational readiness reviews to determine ability of the 62 PHEP jurisdictions to implement plans for distributing and dispensing medicines and medical supplies in response to an incident or exercise requiring MCMs from the Strategic National Stockpile. State public health personnel conduct operational readiness reviews for CRI jurisdictions using CDC guidance. CDC developed the Online Technical Resource and Assistance Center (On-TRAC) to provide state and local public health departments a secure, user-friendly platform for requesting technical assistance. Learn more about On-TRAC

Page last reviewed: April 4, 2022, 12:35 PM