Guidance for Laboratories

Laboratories and other facilities that handle or store infectious and potentially infectious poliovirus materials pose a risk for polioviruses to be re-introduced into communities after eradication. Among samples collected from asymptomatic people living in an area with known poliovirus transmission, or where oral polio vaccination is taking place, as many as 19% of stool samples and 1% of respiratory samples have demonstrated growth of polioviruses.

The WHO Global Action Plan to Minimize Poliovirus Facility–Associated Risk after Type-Specific Eradication of Wild Polioviruses and Sequential Cessation of Oral Poliovirus Vaccine Use (GAPIII)pdf iconexternal icon, endorsed by the World Health Assembly in 2015, describes the requirements for poliovirus containment.

Looking For every Last Poliovirus In Global Sample Collections
Guidance for Laboratories
The U.S. National Authority for Containment (NAC)

The U.S. National Authority for Containment (NAC) strongly encourages facilities to destroy all poliovirus containing samples that are not deemed essential.

If you think you have any of these materials, please contact the U.S. NAC for assistance

Email poliocontainment@cdc.gov or call 404-718-5160.

The NAC can help you:

  • determine if any of your specimens are poliovirus potentially infectious materials
  • distinguish between WPV/VDPV PIM and OPV PIM
  • work with you to capture this information and complete the national poliovirus survey
Page last reviewed: May 11, 2020, 01:15 PM