Important update: Healthcare facilities
CDC has updated select ways to operate healthcare systems effectively in response to COVID-19 vaccination. Learn more
Given new evidence on the B.1.617.2 (Delta) variant, CDC has updated the guidance for fully vaccinated people. CDC recommends universal indoor masking for all teachers, staff, students, and visitors to K-12 schools, regardless of vaccination status. Children should return to full-time in-person learning in the fall with layered prevention strategies in place.
The White House announced that vaccines will be required for international travelers coming into the United States, with an effective date of November 8, 2021. For purposes of entry into the United States, vaccines accepted will include FDA approved or authorized and WHO Emergency Use Listing vaccines. More information is available here.
Travel requirements to enter the United States are changing, starting November 8, 2021. More information is available here.

COVID-19 Vaccines for People with Underlying Medical Conditions

COVID-19 Vaccines for People with Underlying Medical Conditions

Most People with Underlying Medical Conditions Can Get COVID-19 Vaccines

COVID-19 vaccines may be administered to most people with underlying medical conditions, including people with:

Learn more about what you can do when you have been fully vaccinated.

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If you have questions about getting a COVID-19 vaccine, you should talk to your healthcare provider for advice. Inform your vaccination provider about all your allergies and health conditions.

Find a COVID-19 Vaccine

  • The federal government is providing the COVID-19 vaccine free of charge to all people living in the United States, regardless of their immigration or health insurance status.
  • Check with your healthcare provider about whether they offer COVID-19 vaccination.
  • Check your local pharmacy’s website to see if vaccination walk-ins or appointments are available.
  • Contact your state, territorial, local, or tribal health department for more information.

Find a COVID-19 vaccine or booster: Search, text your ZIP code to 438829, or call 1-800-232-0233 to find locations near you.

COVID-19 Vaccines Are Safe for People with Underlying Medical Conditions

Clinical trials show that COVID-19 vaccines are safe and effective in people with underlying medical conditions, including those that place them at increased risk for severe COVID-19 symptoms, compared to people without underlying medical conditions.

Vaccine manufacturers report information from clinical trials, including demographics and underlying medical conditions of people who participated in COVID-19 vaccine trials. You can find additional information on COVID-19 vaccine clinical trials at clinicaltrials.govexternal icon, a database of privately and publicly funded clinical studies conducted around the world. You can help protect yourself and the people around you by getting a COVID-19 vaccine as soon as you can.

Preparing for Your Vaccination

  • Depending on the kind of COVID-19 vaccine you get, you might need a second shot 3 or 4 weeks after your first shot.
  • If you are moderately or severely immunocompromised, you may need to get an additional primary shot.
  • Most people, including those with medical conditions or compromised immune systems, are eligible to get a COVID-19 vaccine booster shot.
  • At your first vaccination appointment, you should get a CDC COVID-19 Vaccination Record card that tells you what COVID-19 vaccine you received, the date you received it, and where you received it. You should bring this card to any COVID-19 vaccination appointment you have after your first dose.
  • You may experience side effects after getting a COVID-19 vaccine. These are normal signs that your body is building protection against COVID-19.
  • Use v-safe to tell CDC about any side effects after each of your COVID-19 vaccination appointments.
Difference between Additional Primary Shot and Booster Shot
  • An additional primary shot is for people who do not build enough or any protection from their primary vaccine series. This appears to be the case for some moderately or severely immunocompromised people who received Pfizer-BioNTech or Moderna COVID-19 vaccines.
  • A booster shot is for people who built enough protection after completing their primary vaccine series, but then that protection decreased over time. Everyone 16 years and older can get a COVID-19 booster shot. Pfizer-BioNTech or Moderna (mRNA COVID-19 vaccines) are preferred in most situations. Although mRNA vaccines are preferred, J&J/Janssen COVID-19 vaccine may be considered in some situations.