Important update: Healthcare facilities
CDC has updated select ways to operate healthcare systems effectively in response to COVID-19 vaccination. Learn more
To maximize protection from the Delta variant and prevent possibly spreading it to others, get vaccinated as soon as you can and wear a mask indoors in public if you are in an area of substantial or high transmission.
UPDATE
Given new evidence on the B.1.617.2 (Delta) variant, CDC has updated the guidance for fully vaccinated people. CDC recommends universal indoor masking for all teachers, staff, students, and visitors to K-12 schools, regardless of vaccination status. Children should return to full-time in-person learning in the fall with layered prevention strategies in place.
UPDATE
The White House announced that vaccines will be required for international travelers coming into the United States, with an effective date of November 8, 2021. For purposes of entry into the United States, vaccines accepted will include FDA approved or authorized and WHO Emergency Use Listing vaccines. More information is available here.

Different COVID-19 Vaccines

Different COVID-19 Vaccines

NOTICE: CDC now recommends that certain people are now eligible to receive a COVID-19 booster shot, including those who received Moderna and Johnson & Johnson/Janssen COVID-19 vaccines. Get more information and read CDC’s media statement.

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Approved and Authorized Vaccines

Below are the vaccines that are approved and authorized in the United States to prevent COVID-19:

Pfizer-BioNTech
Moderna
Johnson & Johnson / Janssen

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Different COVID-19 Vaccines

Vaccines are now widely available. In most cases, you do need an appointment. Do not wait for a specific brand. Learn how to find a COVID-19 vaccine so you can get it as soon as you can.

All currently authorized and recommended COVID-19 vaccines:

CDC does not recommend one vaccine over another.

Pfizer-BioNTech

Moderna

Johnson & Johnson’s Janssen

Pfizer-BioNTech

Who Can Get this Vaccine [1]
People 12 years and older

Moderna

Who Can Get this Vaccine [1]
People 18 years and older

Johnson & Johnson’s Janssen

Who Can Get this Vaccine [1]
People 18 years and older

Pfizer-BioNTech

Number of Shots
2 shots
Given 3 weeks (21 days) apart [2]

Moderna

Number of Shots
2 shots
Given 4 weeks (28 days) apart [2]

Johnson & Johnson’s Janssen

Number of Shots
1 shot

Pfizer-BioNTech

When Fully Vaccinated
2 weeks after your second shot

Moderna

When Fully Vaccinated
2 weeks after your second shot

Johnson & Johnson’s Janssen

When Fully Vaccinated
2 weeks after your shot

Pfizer-BioNTech

Additional Dose
Recommended for moderately to severely immunocompromised people
Given 4 weeks after second shot

Moderna

Additional Dose
Recommended for moderately to severely immunocompromised people
Given 4 weeks after second shot

Johnson & Johnson’s Janssen

Additional Dose
Not recommended at this time

Pfizer-BioNTech

Booster Dose
Recommended for some people who are at higher risk for COVID-19 exposure or severe illness [3]
Given 6 or more months after second shot

Moderna

Booster Dose
Not recommended at this time

Johnson & Johnson’s Janssen

Booster Dose
Not recommended at this time

Vaccine Brand Name
Pfizer-BioNTech

Who Can Get this Vaccine [1]
People 12 years and older

Number of Shots

  • 2 shots
  • Given 3 weeks (21 days) apart [2]

When Fully Vaccinated
2 weeks after your second shot

Additional Dose

Booster Dose

Vaccine Brand Name
Moderna

Who Can Get this Vaccine [1]
People 18 years and older

Number of Shots

  • 2 shots
  • Given 4 weeks (28 days) apart [2]

When Fully Vaccinated
2 weeks after your second shot

Additional Dose

Booster Dose
Not recommended at this time

Vaccine Brand Name
Johnson & Johnson’s Janssen

Who Can Get this Vaccine [1]
People 18 years and older

Number of Shots
1 shot

When Fully Vaccinated
2 weeks after your shot

Additional Dose
Not recommended at this time

Booster Dose
Not recommended at this time

1 If you had a severe allergic reaction (anaphylaxis) or an immediate allergic reaction to any ingredient in the vaccine you are scheduled to receive, you should not get that vaccine. If you have been instructed not to get one type of COVID-19 vaccine, you may still be able to get another type. Learn more information for people with allergies.

2 You should get your second shot as close to the recommended 3-week or 4-week interval as possible.

3 At this time, CDC does not have a recommendation for immunocompromised people to receive both a booster shot and an additional dose.

Vaccine Types

  • Understanding How COVID-19 Vaccines Work
    Learn how the body fights infection and how COVID-19 vaccines protect people by producing immunity. Also see the different types of COVID-19 vaccines that currently are available or are undergoing large-scale (Phase 3) clinical trials in the United States.​
  • COVID-19 mRNA Vaccines
    Information about mRNA vaccines generally and COVID-19 vaccines that use this new technology specifically.
  • Viral Vector COVID-19 Vaccines
    Information about viral vector vaccines generally and COVID-19 vaccines that use this new technology specifically.

Vaccines in Phase 3 Clinical Trials

Large-scale (Phase 3) clinical trials are in progress or being planned for COVID-19 vaccines in the United States. To learn more about U.S. COVID-19 vaccine clinical trials, including vaccines in earlier stages of development, by visiting clinicaltrials.gov.external icon

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For Healthcare and Public Health

COVID-19 Clinical and Professional Resources