Diagnostic confirmation

Source of standard: North American Association of Central Cancer Registriesexternal icon

Source item name: Diagnostic confirmation

Source item number: 490external icon

This variable records the best method of diagnostic confirmation of the cancer being reported at any time in the patient’s history. The rules for coding differ between solid tumors and hematopoietic and lymphoid neoplasms.

Considerations for Use

  • For analyses that include histology, it is recommended to use the following selection statement in the SEER*Stat Selection tab: “Diagnostic confirmation is = to Microscopically confirmed”.
  • Diagnostic confirmation is useful to calculate rates based on microscopically confirmed cancers. Full incidence calculations must also include cases that are only confirmed clinically. The percentage of cases that are “clinically diagnosed only” is an indication of whether case finding includes sources outside of pathology reports.
  • The microscopically confirmed method has the highest priority for diagnostic confirmation. The remaining values were assigned when the presence of cancer was confirmed with multiple diagnostic methods.
  • “Positive histology AND immunophenotyping AND/OR positive genetic studies” (used only for hematopoietic and lymphoid neoplasms M-9590/3-9992/3) was adopted for use beginning with 2010 diagnoses.