HPV-Associated Cancer Statistics

Based on data from 2011 to 2015, about 42,700 HPV-associated cancers occur in the United States each year: about 24,400 among women, and about 18,300 among men. Cervical cancer is the most common HPV-associated cancer among women, and oropharyngeal cancers (cancers of the back of the throat, including the base of the tongue and tonsils) are the most common among men.

HPV-associated cancers are estimated by examining cancer in parts of the body and cancer cell types that are more likely to be caused by HPV. Cancer registries do not collect data on the presence or absence of HPV in cancer tissue at the time of diagnosis.

In general, HPV is thought to be responsible for more than 90% of anal and cervical cancers, about 70% of vaginal and vulvar cancers, and more than 60% of penile cancers. Oropharyngeal cancers traditionally have been caused by tobacco and alcohol, but recent studies show that about 70% of cancers of the oropharynx may be linked to HPV. Many cancers of the oropharynx may be caused by a combination of tobacco, alcohol, and HPV.

Photo of a woman looking at data on a digital tablet
Each year, about 42,700 new cases of cancer are found in parts of the body where human papillomavirus (HPV) is often found. HPV causes about 33,700 of these cancers.
Photo of six people of different ethnicities
The rate of people getting HPV-associated cancers varies by race and ethnicity. See the annual number and rate of HPV-associated cancers by cancer site, sex, and race and ethnicity.
Map of the United States
A map showing the states divided into groups based on the rates at which people were diagnosed with an HPV-associated cancer.
Photo of grandparents, parents, and a baby
Cervical cancer is usually diagnosed at younger ages than other HPV-associated cancers. HPV-associated anal and oropharyngeal cancers generally are diagnosed at slightly younger ages in men than in women.
Page last reviewed: August 29, 2018