Signs and Symptoms

The most common symptoms of uterine cancer are—1 2 3

  • Abnormal vaginal bleeding or discharge.
  • Abnormal pain or pressure in the pelvis.

Uterine cancer should be considered in—

  • Postmenopausal women with any vaginal bleeding.
  • Premenopausal or perimenopausal women who report changes in their bleeding pattern (such as heavy or prolonged bleeding), especially those with polycystic ovary syndrome (PCOS) and/or a history of oligo-ovulation or infertility.
  • Premenopausal or postmenopausal obese women with abnormal bleeding.


1CDC. What Are the Risk Factors for Uterine Cancer?

2DeVita VT Jr, Lawrence TS, Rosenberg SA, DePinho RA, and Weinberg RA. Devita, Hellman, and Rosenberg’s Cancer: Principles and Practice of Oncology (8th ed.). Philadelphia: Lippincott Williams and Wilkins, 2008.

3Schottenfeld D, Fraumeni J Jr. Cancer Epidemiology and Prevention (3rd ed.). Eastbourne, UK; WB Saunders Co., 1982.

Page last reviewed: September 14, 2015