DP19-1905 Guide for Prospective Applicants


April 15, 11:59 PM ET is the application deadline on www.grants.gov.External

Program Goals

CDC’s Cancer Genomics Program aims to develop best practices in education, surveillance, and policy/systems change approaches, and to establish an evidence base for the application of family history and cancer genomics into public health practice.

Recipients of past funding opportunities have demonstrated experience and capacity to accelerate the development of best practices and the evidence base for public health genomics. They have served as a laboratory for the implementation of novel and innovative interventions in family history and cancer genomics. Through the evaluation of activities and strategies, we have worked with our recipients to understand impact and identify best practices for translation and dissemination to other public health programs and organizations.

CDC funds the implementation of public health programs in cancer genomics as a strategy to impact cancer prevention and control by—

  • Maximizing opportunities for cancer prevention.
    • Identifying high-risk individuals and their family members through family history screening for referral to genetic counseling and testing.
    • Educating high-risk individuals on options they can discuss with their provider to modify their cancer risk, including health behavior change (such as smoking cessation, reduced alcohol consumption, maintaining a healthy weight, and engaging in regular physical activity), chemoprevention, and prophylactic surgery.
  • Increasing risk-stratified cancer screening.
    • Recommendations issued by the United States Preventive Services Task Force (USPSTF) for breast, colorectal, and prostate cancer screening highlight the importance of providers taking family history of cancer into account when discussing cancer screening with patients.
    • Individuals at increased risk of cancer due to family history and/or genetic mutations may require screening at earlier ages, higher frequency, or with alternative technologies or modalities.
  • Delivering high-quality cancer care.
    • Genetic counseling and genetic testing (or tumor testing) during the cancer diagnosis process could affect decisions about treatment (such as treatment type and course and prophylactic surgery).
    • Genetic testing results also may affect medical follow-up and future surveillance for cancer recurrence or screening for secondary cancers.
  • Improving health communication.
    • Developing and implementing best practices for numeracy, risk communication, and health and genetic literacy to facilitate improved comprehension from health education efforts for the public and providers.
  • Addressing disparities in access and use.
    • Research indicates that members of racial and ethnic minority groups and those in rural areas have less access to genetic counseling and genetic testing services and are less likely to use these services because of lack of availability or awareness of these services.