HPV-Associated Cancer Statistics

Based on data from 2014 to 2018, about 46,143 HPV-associated cancers occur in the United States each year: 25,719 among women, and 20,424 among men. Cervical cancer is the most common HPV-associated cancer among women, and oropharyngeal cancers (cancers of the back of the throat, including the base of the tongue and tonsils) are the most common among men.

HPV-associated cancers are estimated by examining cancer in parts of the body and cancer cell types that are more likely to be caused by HPV. Cancer registries do not collect data on the presence or absence of HPV in cancer tissue at the time of diagnosis.

In general, HPV is thought to be responsible for more than 90% of anal and cervical cancers, about 70% of vaginal and vulvar cancers, and more than 60% of penile cancers. Oropharyngeal cancers traditionally have been caused by tobacco and alcohol, but recent studies show that about 70% of cancers of the oropharynx may be linked to HPV. Many cancers of the oropharynx may be caused by a combination of tobacco, alcohol, and HPV.

U.S. Cancer Statistics Data Visualizations Tool

The Data Visualizations tool makes it easy for anyone to explore and use the latest official federal government cancer data from United States Cancer Statistics. It includes the latest cancer data covering the U.S. population.

The Data Visualizations tool shows rates for HPV-associated cancers among women, among men, and among women and men combined for all HPV-associated cancers combined and by cancer type.

Photo of a woman accessing a map-based application on her tablet.
Photo of a woman looking at data on a digital tablet

Each year, about 46,000 new cases of cancer are found in parts of the body where human papillomavirus (HPV) is often found. HPV causes about 36,500 of these cancers.

Photo of grandparents, parents, and a baby

Cervical cancer is usually diagnosed at younger ages than other HPV-associated cancers. HPV-associated anal and oropharyngeal cancers generally are diagnosed at slightly younger ages in men than in women.

More Information
United States Cancer Statistics Data Brief

Centers for Disease Control and Prevention. Cancers Associated with Human Papillomavirus, United States, 2014–2018. United States Cancer Statistics Data Brief 2021;26.

Page last reviewed: December 13, 2021