HPV-Associated Cancer Statistics

Based on data from 2012 to 2016, about 44,000 HPV-associated cancers occur in the United States each year: about 25,000 among women, and about 19,000 among men. Cervical cancer is the most common HPV-associated cancer among women, and oropharyngeal cancers (cancers of the back of the throat, including the base of the tongue and tonsils) are the most common among men.

HPV-associated cancers are estimated by examining cancer in parts of the body and cancer cell types that are more likely to be caused by HPV. Cancer registries do not collect data on the presence or absence of HPV in cancer tissue at the time of diagnosis.

In general, HPV is thought to be responsible for more than 90% of anal and cervical cancers, about 70% of vaginal and vulvar cancers, and more than 60% of penile cancers. Oropharyngeal cancers traditionally have been caused by tobacco and alcohol, but recent studies show that about 70% of cancers of the oropharynx may be linked to HPV. Many cancers of the oropharynx may be caused by a combination of tobacco, alcohol, and HPV.

U.S. Cancer Statistics Data Visualizations Tool

The Data Visualizations tool makes it easy for anyone to explore and use the latest official federal government cancer data from United States Cancer Statistics. It includes the latest cancer data covering 100% of the U.S. population.

The Data Visualizations tool shows rates for HPV-associated cancers among women, among men, and among women and men combined.

Photo of a woman accessing a map-based application on her tablet.
Photo of a woman looking at data on a digital tablet
Each year, about 44,000 new cases of cancer are found in parts of the body where human papillomavirus (HPV) is often found. HPV causes about 34,800 of these cancers.
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The rate of people getting HPV-associated cancers varies by race and ethnicity. See the annual number and rate of HPV-associated cancers by cancer site, sex, and race and ethnicity.
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Cervical cancer is usually diagnosed at younger ages than other HPV-associated cancers. HPV-associated anal and oropharyngeal cancers generally are diagnosed at slightly younger ages in men than in women.