Toenail mercury levels are associated with amyotrophic lateral sclerosis (ALS) risk

Affiliates Angeline S. Andrew [1], Celia Y. Chen [2], Tracie A. Caller [3], Rup Tandan [4], Patricia L. Henegan [1], Brian P. Jackson [2], Brenda P. Hall [1], Walter G. Bradley [5], & Elijah W. Stommel [1]


[1] Department of Neurology, Geisel School of Medicine at Dartmouth
[2] Departments of Biological Sciences, Earth Science, Dartmouth College
[3] Cheyenne Regional Medical Center, Medical Specialty Clinic
[4] Department of Neurological Sciences, University of Vermont Medical Center
[5] Department of Neurology, Miller School of Medicine, University of Miami, Miami, FL, USA

Journal Muscle & Nerve
Summary This study sought to measure levels of mercury in toenail samples from persons living with ALS using coupled plasma mass spectrometry. persons living with ALS had significantly higher mercury toenail levels (OR = 2.49; 95% CI: 1.18-5.80) compared to controls after adjusting for age and gender.
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