AFM Cases in U.S.
There are 22 confirmed cases so far in 2019 (CA [8 cases], GA, MD [3 cases], NC [2 cases], NE, PA, TX [4 cases], UT, WV) out of 102 reports of PUIs.
No deaths were reported during the acute illness of patients with confirmed AFM who had limb weakness onset in 2018; however, there were two reports of patients confirmed with AFM in 2018 who had expired months after limb weakness onset. We have also learned of deaths in cases confirmed in previous years.
- There have been 236 confirmed cases of AFM in 41 states in 2018.
- Note: These 236 confirmed cases are among the total of 385 reports that CDC received of patients under investigation (PUIs).
- Most patients under investigation have been classified, but CDC and state and local health departments are still investigating some of the PUIs.
|State||AFM confirmed cases|
|New York State||7|
|New York City||4|
We defer to the states to release additional information on cases as they choose.
There have been 590 confirmed cases since CDC began tracking AFM in August of 2014.
CDC has been thoroughly investigating the AFM cases that have occurred since 2014, when we first noted a large number of cases being reported. We have seen increases in AFM cases, mostly in young children, every two years since 2014.
|Year||Confirmed Cases||States with Confirmed Cases|
|2016||153||39 (and DC)|
^ The case counts represent only those cases for which information has been sent to and confirmed by CDC. Case counts are preliminary and subject to change
Most patients had onset of AFM between August and October, with increases in AFM cases every two years since 2014. At this same time of year, many viruses commonly circulate, including enteroviruses, and will be temporally associated with AFM.
The graph shows the number of AFM cases confirmed by CDC from August 2014 through October 4, 2019, with onset of the condition through August 31, 2019.
^ Confirmed AFM cases that CDC has been made aware of as of October 4, 2019 with onset of the condition through August 31, 2019. The case counts are subject to change.
* The data shown from August 2014 to July 2015 are based on the AFM investigation case definition: onset of acute limb weakness on or after August 1, 2014, and a magnetic resonance image (MRI) showing a spinal cord lesion largely restricted to gray matter in a patient age ≤21 years.
† The data shown from August 2015 to present are based on the AFM case definition adopted by the Council of State and Territorial Epidemiologists (CSTE): acute onset of focal limb weakness and an MRI showing spinal cord lesion largely restricted to gray matter and spanning one or more spinal segments, regardless of age.
For more information, visit the Case Definitions page.
It is currently difficult to interpret trends of the AFM data. Collecting information about PUIs for AFM is relatively new. There may initially be more variability in the AFM data from year to year, making it difficult to interpret or compare case counts between years.