CDC Strategic Framework and Priorities

Using Science and Innovation to Prevent, Detect, and Respond

CDC’s Strategic Framework consists of five core capabilities that enable the agency’s three strategic priorities, all united behind one mission: protect America’s safety, health, and security. Our work is underscored by the agency’s Pledge to the American People.

Core Capability, Strategic Priority, and Mission

Strategic Framework and Priorities

5 Core Capabilities

World-Class data and analytics

State-of-the-art laboratory capacity

Elite public health expertise

Responding to Outbreaks at their source

Global Capacity and domestic preparedness

3 Strategic Priorities

Securing Global Health and America’s Preparedness

Eliminating Disease

Ending Epidemics

1 Mission

Protecting America’s safety, health, and security

CDC’s Strategic Framework is Based on Action Plans and Detailed Measures of Success.

Examples Include:

Securing Global Health and America’s Preparedness

  • Rapid Response – By 2023, double the number of rostered and deployable CDC Global Rapid Response Team surge staff as compared to 2020.
  • Vector-Borne Diseases – Reduce by 75% cases of Rocky Mountain spotted fever in U.S. tribal communities.
  • Global Health – Zero countries with wild poliovirus.

Eliminating Disease

  • HIV – Eliminate new HIV infections.
  • Vaccine-Preventable – By 2023, reduce the magnitude of the disparity in influenza vaccination among Black and Hispanic populations by 10%.
  • Hepatitis C – Reduce hepatitis C-related deaths by 20% by 2024.
  • Maternal Mortality – Reduce the maternal mortality rate by 50% by 2025 (from 17.4 deaths per 100,000 live births to 8.7 deaths per 100,000 live births).

Ending Epidemics

  • Opioids – Stop the rise of U.S. drug overdose mortality by 2025.
  • Opioids – Reduce opioid prescribing by at least 10% by 2025 to prevent harms associated with prescription opioid misuse.
  • Influenza – By 2021, increase flu vaccination coverage rates among children and pregnant women to 65%.
  • ​Antibiotics – Reduce by 50% inappropriate antibiotic use in outpatient settings by 2021.
  • Diabetes – Reduce the number of new diabetes diagnoses from 1.4 million in 2018 to 1.1 million per year by 2025.
A Closer Look at CDC’s Core Capabilities and Strategic Priorities
CDC’s 5 Core Capabilities

World-Class Data and Analytics

Develop and deploy world-class data and analytics, which are critical assets to meeting today’s and tomorrow’s health challenges. Data is the foundation of CDC’s work. As a strategic asset, the data CDC generates and uses needs to be timely, accurate, and usable.

State-of-the-Art Lab Capacity

As the reference lab to the world, we must maintain state-of-the-art laboratory capacity. CDC is a world leader in laboratory science, which is fundamental to CDC’s work. Conducted to the highest standards of safety and quality, this science informs public health action.

Elite Public Health Expertise

Elite public health expertise ensures we have the capacity to address complex diseases and swiftly respond to new threats. To accomplish our mission, CDC needs to maintain an elite, highly trained, cutting edge, deployable, and flexible scientific and programmatic workforce that represents diverse personal and disciplinary backgrounds to increase understanding and partnership with all those we serve.

Responding to Outbreaks at Their Source

Quickly respond to outbreaks at their source, both domestic and abroad. CDC’s foremost responsibility is to respond to outbreaks, which are becoming ever more complex and frequent, to protect Americans’ health, save lives, and protect livelihoods. The world counts on CDC to implement appropriate and immediate early interventions, which could prevent an aggressive outbreak from becoming an epidemic, and prevent an epidemic in a country or region from developing into a worldwide pandemic.

Global Capacity and Domestic Preparedness

Build on the current foundation for strong global health capacity and domestic preparedness. State and local expertise and a strategic global footprint refocused to the highest-risk regions will help ensure an adaptable, resilient, better coordinated system, and better prepared countries that can address disease threats at their source.

CDC’s 3 Strategic Priorities

Securing Global Health and America’s Preparedness
By stopping the spread of pandemic contagions, addressing public health terror threats, and protecting people from vector-borne diseases.

Eliminating Disease
By controlling vaccine-preventable disease, targeting Hepatitis C, and reducing the maternal mortality rate.

Ending Epidemics
Such as HIV, decreasing opioid overdoses, improving strategies and interventions to stem seasonal influenza, developing and deploying new answers for antibiotic resistance, and reducing new incidents of diabetes.

CDC’s Mission: Protect America’s Safety, Health, and Security

Our strategic priorities are also enabled by unique expertise and interdependent capabilities, including strategic communications, operational excellence built upon a foundation of equal employment opportunity, partnerships across all the populations we serve, and culturally appropriate stakeholder engagement.

Page last reviewed: June 8, 2021