ABCs Report: Group B Streptococcus, 2017
April 5, 2019: Content on this page kept for historical reasons.
Active Bacterial Core Surveillance (ABCs): Emerging Infections Program Network
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ABCs Areas
California (3 county San Francisco Bay area); Colorado (5 county Denver area); Connecticut; Georgia (20 county); Maryland; Minnesota; New Mexico; New York (15 county Rochester and Albany areas); Oregon (3 county Portland area); Tennessee (20 counties)
ABCs Population
The surveillance areas represent 37,535,943 persons and 432,895 live births. Source: National Center for Health Statistics bridged race vintage 2017 postcensal file and 2017 natality data from National Center for Health Statistics (NCHS) 1.
ABCs Case Definition
Invasive group B streptococcal disease: isolation of Group B Streptococcus from a normally sterile site in a resident of a surveillance area in 2017. Early‑onset cases occur at < 7 days of age and late‑onset occur between 7 and 89 days of age.
ABCs Methodology
ABCs personnel routinely contacted all microbiology laboratories serving acute care hospitals in their area to identify cases. Standardized case report forms that include information on demographic characteristics, clinical syndrome, and outcome of illness were completed for each identified case. From select surveillance areas, WGS testing was conducted for all group B Streptococcus isolates, which includes deduction of capsular serotype and MIC predictions, including PBP2x typing to detect decreased beta lactam susceptibility. A strategic subset of isolates was targeted for conventional MIC determination. Regular laboratory audits assessed completeness of active surveillance and detected additional cases.
Rates of early‑onset and late‑onset group B streptococcal disease were calculated using live birth estimates for 2017. All other rates were calculated using population estimates for 2017 from the bridged-race vintage 2017 postcensal file. For national estimates of cases, race‑ and age‑specific rates of disease were applied from the aggregate surveillance area to the age and racial distribution of the 2017 U.S. population and to the 2017 live birth estimates for early-onset and late-onset disease. Cases with missing data, excluding ethnicity, were multiply imputed using sequential regression imputation methods.¶
Reported ABCs Profiles
| Race | No. | (Rate*) |
|---|---|---|
| White | 2,599 | (9.6) |
| Black | 815 | (12.0) |
| Other | 241 | (6.8) |
* Per 100,000 population for ABCs areas
| Ethnicity | No. | (Rate*) |
|---|---|---|
| Hispanic | 349 | (6.7) |
| Non-Hispanic | 2,664 | — |
| Unknown | 642 | — |
* Per 100,000 population for ABCs areas
| Age (years) | Cases No. (Rate*) |
Deaths No. (Rate*) |
|---|---|---|
| < 1 | 245 (55.2) | 11 (2.48) |
| 1 | 1 (0.2) | 0 (0.00) |
| 2‑4 | 1 (0.1) | 1 (0.07) |
| 5‑17 | 18 (0.3) | 0 (0.00) |
| 18‑34 | 222 (2.5) | 6 (0.07) |
| 35‑49 | 542 (7.3) | 28 (0.38) |
| 50‑64 | 1,059 (14.3) | 63 (0.85) |
| 65-74 | 756 (23.2) | 52 (1.59) |
| 75-84 | 520 (34.0) | 29 (1.90) |
| ≥85 | 291 (41.6) | 39 (5.58) |
| Total | 3,655 (9.7) | 229 (0.61) |
* Per 100,000 population for ABCs areas
| Race | Early Onset No. (Rate*) |
Late Onset No. (Rate*) |
|---|---|---|
| White | 49 (0.17) | 73 (0.25) |
| Black | 41 (0.43) | 54 (0.56) |
| Other | 11 (0.24) | 6 (0.13) |
| Total | 101 (0.23) | 133 (0.31) |
* Per 1,000 live birth for ABCs areas
National Estimates of Invasive Disease
Early Onset Cases: 830 (0.22/1,000 live births)
Late Onset Cases: 1,110 (0.29/1,000 live births)
Total Cases: 31,850 (9.8/100,000 population)
Deaths: 2,030 (0.62/100,000 population)
Reference
- National Center for Health Statistics. Vital Statistics Birth Data File, 2017. All-county file data file and documentation. 2017.
Citation
Centers for Disease Control and Prevention. 2017. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Group B Streptococcus, 2017.