ABCs Report: Group B Streptococcus, 2015

March 8, 2016: Content on this page kept for historical reasons.

Active Bacterial Core Surveillance (ABCs): Emerging Infections Program Network

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Surveillance Note

Missing race (n=262) data were multiply imputed using sequential regression imputation methods.

ABCs Areas

California (3 county San Francisco Bay area); Colorado (5 county Denver area); Connecticut (children < 1 year); Georgia (20 county); Maryland; Minnesota; New Mexico; New York (15 county Rochester and Albany areas); Oregon (3 county Portland area); Tennessee (20 counties)

ABCs Population

The surveillance areas represent 33,415,379 persons and 437,266 live births.

Source: National Center for Health Statistics bridged race vintage 2015 postcensal file and 2013 state vital records

ABCs Case Definition

Invasive group B streptococcal disease: isolation of Group B Streptococcus from a normally sterile site in a resident of a surveillance area in 2015. Early-onset cases occur at < 7 days of age and late-onset occur between 7 and 89 days of age.

ABCs Methodology

ABCs personnel routinely contacted all microbiology laboratories serving acute care hospitals in their area to identify cases. Standardized case report forms that include information on demographic characteristics, clinical syndrome, and outcome of illness were completed for each identified case.  Regular laboratory audits assessed completeness of active surveillance and detected additional cases.

Rates of early-onset and late-onset group B streptococcal disease were calculated using live birth estimates for 2013. All other rates were calculated using population estimates for 2015 from the bridged-race vintage 2015 postcensal file. For national estimates of cases, race- and age-specific rates of disease were applied from the aggregate surveillance area to the age and racial distribution of the 2015 U.S. population and to the 2013 live birth estimates for early-onset and late-onset disease. Cases with missing data, excluding ethnicity, were multiply imputed using sequential regression imputation methods.

Reported ABCs Profiles

Reported ABCs Profiles
Race No. (Rate*)
White 2,074 (8.6)
Black 708 (11.5)
Other 174 (5.5)

* Per 100,000 population for ABCs areas

Reported ABCs Profiles by ethnicity, number, and rate
Ethnicity No. (Rate*)
Hispanic 254 (5.7)
Non-Hispanic 2,155
Unknown 547

* Per 100,000 population for ABCs areas

Reported ABCs Profiles by age, cases, rates, and deaths
Age (years) Cases
No. (Rate*)
Deaths
No. (Rate*)
< 1 275 (61.3) 20 (4.46)
1 4 (1.0) 0 (0.00)
2-4 1 (0.1) 1 (0.08)
5-17 11 (0.2) 1 (0.02)
18-34 176 (2.2) 3 (0.04)
35-49 392 (5.9) 12 (0.18)
50-64 919 (14.0) 56 (0.85)
65-74 532 (19.8) 29 (1.08)
75-84 394 (30.9) 31 (2.43)
≥ 85 252 (42.6) 28 (4.73)
Total 2,956 (8.9) 181 (0.54)

* Per 100,000 population for ABCs areas

Reported ABCs Profiles by race, and onset
Race Early-Onset
No. (Rate*)
Late-Onset
No. (Rate*)
White 45 (0.15) 76 (0.25)
Black 53 (0.57) 63 (0.68)
Other 4 (0.09) 11 (0.25)
Total 102 (0.23) 150 (0.34)

* Per 1,000 live birth for ABCs areas

National Estimates of Invasive Disease

Early Onset Cases: 840 (0.21/1,000 live births)
Late Onset Cases: 1,265 (0.32/1,000 live births)
Total Cases: 28,550 (8.9/100,000 population)
Deaths: 1,770 (0.55/100,000 population)

Healthy People 2020 Update

Early-Onset Disease

Objective: Decrease the incidence of invasive early-onset group B streptococcal disease to 0.25 cases per 1,000 live births.

Reported ABCs Profiles by race, objective, and rate
Race 2020 Objective 2015 Rate*
White 0.25/1,000 0.15/1,000
Black 0.25/1,000 0.57/1,000
Other 0.25/1,000 0.09/1,000
Total 0.25/1,000 0.23/1,000

* Per 1,000 U.S. live births

Citation

Centers for Disease Control and Prevention. 2015. Active Bacterial Core Surveillance Report, Emerging Infections Program Network, Group B Streptococcus, 2015.

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Page last reviewed: March 23, 2017 (archived document)