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Questions and Answers about the ABCs Isolate Bank

Why is it of interest?

Of outstanding value to researchers, the Active Bacterial Core surveillance (ABCs) Isolate Bank contains carefully collected and preserved isolates and crucial laboratory, clinical, and demographic data. These factors can help further in-depth research in a variety of fields, without typical limitations. This isolate bank offers unique research opportunities to investigate scientific questions extending beyond routine surveillance.

Where are isolates stored?

Isolates are stored in a restricted-access facility in Lawrenceville, Georgia, with 24-hour monitoring. All specimen storage units are equipped with computerized climate control sensors and are regularly monitored. The shipping and handling process is also executed with maximum professionalism and detailed care.

How can my institution or I have access to the isolates?

Requests for isolates are reviewed by the isolate bank custodians (at CDC) prior to approval and release. CDC strictly enforces a limited distribution policy that prohibits the secondary distribution of ABCs isolates to third-party researchers. Currently, there is a $80 processing fee. Learn how to request isolates by visiting the Guidelines for Requesting Isolates webpage.

Which data are available?

Group A Streptococcus

  • Year of isolation
  • emm type and presence/absence of sof gene
  • Presence/absence of severe infections (e.g., necrotizing fasciitis or streptococcal toxic shock syndrome)
  • Minimal inhibitory concentration (MIC) testing results to commonly used antibiotics

Group B Streptococcus

  • Year of isolation
  • Perinatal syndrome (early-onset, late-onset, pregnancy-associated)
  • Source (cerebrospinal fluid (CSF), blood, other)
  • Age group
  • Serotype
  • MIC testing results to commonly used antibiotics

Streptococcus pneumoniae

  • Year of isolation
  • Age groups
  • Source (CSF, blood, other)
  • Serotype
  • MIC testing results to commonly used antibiotics
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