Welcome to the Vaccines and Immunizations website.
Skip directly to the search box, site navigation, or content.

Department of Health and Human Services
Centers for Disease Control and Prevention


Vaccines & Immunizations

Vaccines and Preventable Diseases:

Tetanus (Lockjaw) Vaccination

Tetanus (lockjaw) is a serious disease that causes painful tightening of the muscles, usually all over the body. It can lead to "locking" of the jaw so the victim cannot open his mouth or swallow. Tetanus leads to death in about 1 in 10 cases. Several vaccines are used to prevent tetanus among children, adolescents, and adults including DTaP, Tdap, DT, and Td.

Tetanus vaccination

What You Should Know

About the Disease

top of page

Vaccine Information

Diphtheria, Tetanus, and Pertussis Vaccines

There are four combination vaccines used to prevent diphtheria, tetanus and pertussis: DTaP, Tdap, DT, and Td. Two of these (DTaP and DT) are given to children younger than 7 years of age, and two (Tdap and Td) are given to older children and adults. Several other combination vaccines contain DTaP along with other childhood vaccines.

Children should get 5 doses of DTaP, one dose at each of the following ages: 2, 4, 6, and 15-18 months and 4-6 years. DT does not contain pertussis, and is used as a substitute for DTaP for children who cannot tolerate pertussis vaccine.

Td is a tetanus-diphtheria vaccine given to adolescents and adults as a booster shot every 10 years, or after an exposure to tetanus under some circumstances. Tdap is similar to Td but also containing protection against pertussis. A single dose of Tdap is recommended for adolescents 11 or 12 years of age, or in place of one Td booster in older adolescents and adults age 19 through 64.

[Upper-case letters in these abbreviations denote full-strength doses of diphtheria (D) and tetanus (T) toxoids and pertussis (P) vaccine. Lower-case “d” and “p” denote reduced doses of diphtheria and pertussis used in the adolescent/adult-formulations. The “a” in DTaP and Tdap stands for “acellular,” meaning that the pertussis component contains only a part of the pertussis organism.]

top of page

Vaccine Safety

As with all vaccines, there can be minor reactions, including pain and redness at the injection site, headache, fatigue or a vague feeling of discomfort.

top of page

Who Should Not be Vaccinated?

top of page

For Health Professionals

Clinical Information on Tetanus

top of page

top of page

References and Resources

top of page

Provider Education
  • 2009 Clinical education slide setExternal Web Site Policy Adobe Acrobat print-friendly PowerPoint file [PPT - 122KB] Updated May 2009
    from the 11th edition "Epidemiology and Prevention of Vaccine-Preventable Diseases" course
  • Podcasts
    Immunization-related podcasts; none specifically on tetanus

top of page

Materials for Patients

top of page

External Web Site Policy This symbol means you are leaving the CDC.gov Web site. For more information, please see CDC's Exit Notification and Disclaimer policy.

File Formats: All viewers, players, and plug-ins used on this site can be downloaded from the file formats page. (For example: Adobe Acrobat Reader for pdf files, Windows Media Player for audio and video files, PowerPoint Viewer for presentation slides, etc.)

This page last modified on June 12, 2009
Content last reviewed on May 18, 2009
Content Source: National Center for Immunization and Respiratory Diseases

Quick Links

Also Known As & Abbreviations

Safer Healthier People

Centers for Disease Control and Prevention 1600 Clifton Rd, Atlanta, GA 30333, U.S.A
Public Inquiries: 1-800-CDC-INFO (232-4636); 1-888-232-6348 (TTY)

Vaccines and Immunizations