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Department of Health and Human Services
Centers for Disease Control and Prevention


Vaccines & Immunizations

Vaccines and Preventable Diseases:

Pertussis (Whooping Cough) Vaccination
Pronounced (per-TUS-iss)

Whooping cough — known medically as pertussis — is a highly contagious respiratory tract infection. Although it initially resembles an ordinary cold, whooping cough may eventually turn more serious, particularly in infants. Whooping cough is most contagious before the coughing starts. The best way to prevent it is through vaccinations. The childhood vaccine is called DTaP. The whooping cough booster vaccine for adolescents and adults is called Tdap. Both protect against whooping cough, tetanus, and diphtheria.

Pertussis vaccination

Pertussis Outbreaks 2010
Through July 2010, several states have reported an increase in cases and/or localized outbreaks of pertussis, including a state-wide epidemic in California. Localized outbreaks are not uncommon and occur throughout the year. Over the last 5 years, 8,000-25,000 cases of pertussis were reported per year in the United States. Everyone should make sure they are up to date with pertussis vaccinations — DTaP vaccine for infants and children and Tdap booster for adolescents and adults.

See Notes from the Field: Pertussis --- January – June, 2010. MMRW: 9 July 2010 / 59(26);817.

Resources for Healthcare Providers

Resources for Parents and Patients

What You Should Know

About the Disease

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Vaccine Information
Diphtheria, Tetanus, and Pertussis Vaccines

There are several formulations of vaccines used to prevent diphtheria, tetanus and pertussis. Some are combined with vaccines to prevent other diseases and reduce the total number of shots that someone receives at one office visit. In the U.S., DTaP, Tdap, and Td vaccines are most commonly used. One of these (DTaP) is given to children younger than 7 years of age, and two (Tdap and Td) are given to older children and adults.

Children should get 5 doses of DTaP, one dose at each of the following ages: 2, 4, 6, and 15-18 months and 4-6 years.

Td is a tetanus-diphtheria vaccine given to adolescents and adults as a booster shot every 10 years, or after an exposure to tetanus under some circumstances. Tdap is similar to Td but also containing protection against pertussis. A single dose of Tdap is recommended for adolescents 11 or 12 years of age, or in place of one Td booster in older adolescents and adults age 19 through 64.

(Upper-case letters in these abbreviations denote full-strength doses of diphtheria (D) and tetanus (T) toxoids and pertussis (P) vaccine. Lower-case “d” and “p” denote reduced doses of diphtheria and pertussis used in the adolescent/adult-formulations. The “a” in DTaP and Tdap stands for “acellular,” meaning that the pertussis component contains only a part of the pertussis organism.)

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Beliefs & Concerns

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Vaccine Safety

As with all vaccines, there can be minor reactions, including pain and redness at the injection site, headache, fatigue or a vague feeling of discomfort.

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Who Should Not be Vaccinated?

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For Health Professionals

Clinical Information on Pertussis

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Vaccine Recommendations
Health officials now recommend that adults and adolescents receive a Tdap booster vaccine to protect against whooping cough. It is especially important for those in contact with infants younger than 12 months of age.  Tdap booster is recomended instead of the previously recommended Td (tetanus-diphtheria) booster.

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References and Resources

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Provider Education

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Materials for Patients

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This page last modified o August 26, 2010
Content last reviewed on June 1, 2007
Content Source: National Center for Immunization and Respiratory Diseases

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Vaccines and Immunizations