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IIS: Vaccine Products That Correspond to Multiple CPT/CVX Codes

Updated: May 20, 2009

For CPT™ 1999, the Vaccines/Toxoids section of codes was substantially revised. Multiple vaccine codes for the same vaccine type were created in several cases to reflect differences in formulations, dosages, and immunization schedules. These differences are already generally reflected in the CVX codes for use in the HL7 data transmission standard by immunization registries. In order to assist providers and immunization registry developers in the accurate coding of vaccine products administered, the products currently available in the U.S. for Haemophilus influenzae type b, hepatitis B, hepatitis A, influenza virus, and typhoid vaccines are listed here and mapped to the appropriate CPT™ 2001 and CVX codes. Questions may be directed to Robert Savage at hzv3@cdc.gov (608)233-6129. Updates to this information will be made available at www.cdc.gov/vaccines/programs/iis/

Disclaimer: All attempts have been made to verify the accuracy of this information, but it should not be relied upon for clinical decision-making. No endorsement of the manufacturers or products listed here is implied. CPT™ codes are copyright by the American Medical Association.

Haemophilus influenzae type b (Hib)

Haemophilus influenzae type b (Hib)
conjugate vaccines
CPT CVX Conjugate Formulation Schedule Brand Name Manufacturer
90645 47 HbOC (diphtheria CRM197 protein/oligosaccharide) 4 doses HibTITER® Wyeth-Ayerst
90646 46 PRP-D (diphtheria toxoid) booster use only ProHIBiT® Aventis Pasteur Inc.
90648 48 PRP-T (tetanus toxoid) 4 doses ActHIB® OmniHIB® Aventis Pasteur Inc. GlaxoSmithKline
90647 49 PRP-OMP (outer membrane protein) 3 doses PedvaxHIB® Merck & Co., Inc.
In the Hib CPT code descriptors, information about the schedule is included to help providers identify the correct code. This does not necessarily mean that the number of doses specified is required to be given. For children who start the Hib immunization series late, fewer doses may be required. For children who start on time, four doses (at 2, 4, 6, 12-15 months) is the recommended schedule when using HbOC or PRP-T conjugates. Three doses (at 2, 4, 12-15 months) is the recommended schedule when using PRP-OMP conjugates. PRP-D conjugate is only appropriate for the booster dose at 12-15 months.

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Hepatitis B vaccines

Engerix-B® (GlaxoSmithKline)
CPT CVX Formulation Dosage/Volume (Schedule) Appropriate for...
90746 43 adult dose 20 mcg/1.0 mL adults >19 years
90747 44 dialysis or immunosuppressed dose 40 mcg/2.0 mL (4 dose schedule) adult hemodialysis or immunocomprimised
90744 08 pediatric/ adolescent dose 10 mcg/0.5 mL all infants, children, and adolescents

** formulation discontinued as of August 1998 ^^ formulation re-named as of August 1998 ~~2 dose schedule, adult formulation, for adolescents was approved by FDA in September 1999

For CPT 2001, CPT code 90743 was added for the the 2-dose schedule of the adult formulation. It is recommended to use CPT code 90743 and CVX code 43 for adolescents who receive the 2- dose schedule of the adult formulation and CPT code 90746 and CVX code 43 for adults who receive the 3-dose schedule of the adult formulation.

Because of the 1998 change by Merck, CPT codes 90744 and 90745 and CVX codes 08 and 42 were ambiguous. CPT code 90745 was deleted in CPT 2000. It is recommended to use CPT code 90744 and CVX code 08 for all pediatric/adolescent Hepatitis B vaccine products.

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Hepatitis A vaccines

Havrix® (GlaxoSmithKline)
CPT CVX Formulation Dosage/Volume Schedule
90632 52 adult 1440 ELU/1.0 mL 2 doses
90633 83 pediatric/adolescent 720 ELU/0.5 mL 2 doses
90634 84 pediatric/adolescent 360 ELU/0.5 mL 3 doses

VAQTA® (Merck & Co., Inc.)
CPT CVX Formulation Dosage/Volume Schedule
90632 52 adult 50 U/1.0 mL 2 doses
90633 83 pediatric/adolescent 25 U/0.5 mL 2 doses

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Influenza virus vaccines (2000-2001 formulations)

CPT CVX Formulation Dosage/
Volume (Schedule)
Appropriate for... Brand Name Manufacturer
90658 15 split virus 0.5mL 3 years Fluzone®split
Fluvirin®
Fluogen®
Flushield®
Aventis Pasteur Inc.
PowerJect
Parkedale
Wyeth-Ayerst
90657 15 split virus 0.25mL 6-35 months Fluzone®split
Fluvirin®
Fluogen®
Flushield®
Aventis Pasteur Inc.
PowerJect
Parkedale
Wyeth-Ayerst
90659 16 whole virus 0.5mL > 12 years Fluzone®whole Aventis Pasteur Inc.

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Typhoid vaccines

CPT CVX Formulation Brand Name Manufacturer
90690 25 Live, Oral, Ty21a capsules VIVOTIF BERNA® Berna Products (Swiss Serum and Vaccine Institute)
90693 53 Acetone- Inactivated/Killed, Dried (AKD) generic (available only to military) Wyeth-Ayerst
90691 101 Vi capsular polysaccharide (ViCPs) TYPHIM Vi® Aventis Pasteur Inc.
90692 41 Heat- & Phenol- Inactivated (H-P) generic Wyeth-Ayerst

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This page last modified on May 20, 2009
Content last reviewed on May 20, 2009
Content Source: National Center for Immunization and Respiratory Diseases

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