A precaution is a condition in a vaccine recipient that might increase the risk for a serious adverse reaction or that might compromise the ability of the vaccine to produce immunity. According to the ACIP recommendations, vaccination should be deferred when a precaution is present. However, yellow fever vaccination can be considered in these situations if travel to an endemic area is unavoidable and the benefits of vaccination outweigh the risks. Note that the ACIP considers moderate to severe acute illness, with or without fever, as a precaution to administration of all vaccines.
Precautions to yellow fever vaccine administration are:
Asymptomatic HIV infection with moderately decreased CD4+ counts
Adults aged 60 years or older
Infants aged 6–8 months
For specific guidance in these situations, follow the recommendations of the ACIP or contact your state health department. Vaccination recommendations also are available at 1-800-CDC-INFO.