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Reported Tuberculosis in the United States, 2012

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Table 22: Epidemiologic Characteristics of Cases in GENType Clusters1 by Alert Levels Based on Log-likelihood Ratios (LLR)2: United States, 2010–2012

Case Characteristics Unique Alert Levels for Clustered Cases3
Clustered Non-alerted
(LLR <5)
Medium (LLR 5 – <10) High (LLR ≥10)
No. (%) No. (%) No. (%) No. (%) No. (%)

Total

17,659

(78.9)

4,723

(21.1)

2,600

(55.0)

1,089

(23.1)

1,034

(21.9)

Race and Ethnicity

Hispanic or Latino

4,907

(77.3)

1,442

(22.7)

946

(65.6)

313

(21.7)

183

(12.7)

American Indian/Alaska Native

175

(51.5)

165

(48.5)

22

(13.3)

43

(26.1)

100

(60.6)

Asian

5,794

(88.0)

791

(12.0)

659

(83.3)

89

(11.2)

43

(5.4)

Black or African American

3,484

(69.3)

1,546

(30.7)

623

(40.3)

406

(26.3)

517

(33.4)

Native Hawaiian/Other Pacific Islander

91

(57.2)

68

(42.8)

26

(38.2)

27

(39.7)

15

(22.1)

White

2,869

(81.1)

671

(18.9)

302

(45.0)

203

(30.2)

166

(24.7)

Multiple Race

300

(91.5)

28

(8.5)

17

(60.7)

3

(10.7)

8

(28.6)

Unknown or Missing 

39

(76.5)

12

(23.5)

5

(41.7)

5

(41.7)

2

(16.7)

Age Group (Years)

0–4

69

(29.7)

163

(70.3)

76

(46.6)

57

(35.0)

30

(18.4)

5–14

122

(62.6)

73

(37.4)

50

(68.5)

14

(19.2)

9

(12.3)

15–24

1,762

(73.8)

625

(26.2)

355

(56.8)

159

(25.4)

111

(17.8)

25–44

5,745

(78.7)

1,552

(21.3)

846

(54.5)

361

(23.3)

345

(22.2)

45–64

5,365

(75.5)

1,744

(24.5)

891

(51.1)

391

(22.4)

462

(26.5)

≥65

4,593

(89.1)

565

(10.9)

382

(67.6)

106

(18.8)

77

(13.6)

Unknown

3

(75.0)

1

(25.0)

0

0.0

1

(100.0)

0

0.0

Origin of Birth

U.S-born

5,442

(66.4)

2,755

(33.6)

1,122

(40.7)

753

(27.3)

880

(31.9)

Foreign-born

12,203

(86.2)

1,958

(13.8)

1,475

(75.3)

335

(17.1)

148

(7.6)

Unknown or Misssing

14

(58.3)

10

(41.7)

3

(30.0)

1

(10.0)

6

(60.0)

Disease Site

Pulmonary Only

12,129

(76.9)

3,635

(23.1)

1,966

(54.1)

857

(23.6)

812

(22.3)

Extrapulmonary

3,208

(86.8)

487

(13.2)

300

(61.6)

101

(20.7)

86

(17.7)

Both

600

(20.6)

2,308

(79.4)

334

(55.7)

131

(21.8)

135

(22.5)

Unknown

14

(93.3)

1

(6.7)

0

0.0

0

0.0

1

(100.0)

Sputum Smear

Positive

7,907

(75.6)

2,550

(24.4)

1,364

(53.5)

617

(24.2)

569

(22.3)

Negative

7,139

(81.2)

1,647

(18.8)

940

(57.1)

346

(21.0)

361

(21.9)

Not Done

2,592

(83.2)

524

(16.8)

295

(56.3)

126

(24.0)

103

(19.7)

Unknown or Missing

21

(91.3)

2

(8.7)

1

(50.0)

0

0.0

1

(50.0)

Cavitary disease

Yes

263

(72.1)

102

(27.9)

49

(48.0)

30

(29.4)

23

(22.6)

No

1,634

(79.2)

430

(20.8)

240

(55.8)

88

(20.5)

102

(23.7)

Unknown or Missing

411

(85.8)

68

(14.2)

45

(66.2)

13

(19.1)

10

(14.7)

Homeless Within Past Year

Yes

748

(56.5)

575

(43.5)

192

(33.4)

95

(16.5)

288

(50.1)

No

16,732

(80.3)

4,102

(19.7)

2,379

(58.0)

982

(23.9)

741

(18.1)

Unknown or Missing

179

(79.6)

46

(20.4)

29

(63.0)

12

(26.1)

5

(10.9)

Excess Alcohol Use Within the Past Year

Yes

1,903

(63.3)

1,104

(36.7)

447

(40.5)

258

(23.4)

399

(36.1)

No

15,416

(81.4)

3,527

(18.6)

2,100

(59.5)

809

(22.9)

618

(17.5)

Unknown or Missing

340

(80.2)

92

(21.8)

53

(57.6)

22

(23.9)

17

(18.5)

Injecting Drug Use Within Past Year

Yes

200

(61.5)

125

(38.5)

59

(47.2)

25

(20.0)

41

(32.8)

No

17,111

(79.2)

4,490

(20.8)

2,484

(55.3)

1,042

(23.2)

964

(21.5)

Unknown or Missing

348

(76.3)

108

(23.7)

57

(52.8)

22

(20.4)

29

(26.8)

Non-Injecting Drug Use Within Past Year

Yes

958

(56.9)

725

(43.1)

292

(40.3)

178

(24.5)

255

(35.2)

No

16,329

(80.8)

3,890

(19.2)

2,250

(57.8)

890

(22.9)

750

(19.3)

Unknown or Missing

372

(77.5)

108

(22.5)

58

(53.7)

21

(19.4)

29

(26.9)

Resident of a Correction Facility at the Time of Diagnosis

Yes

646

(71.9)

252

(28.1)

125

(49.6)

54

(21.4)

73

(29.0)

No

16,888

(79.2)

4,434

(20.8)

2,450

(55.2)

1,028

(23.2)

956

(21.6)

Unknown or Missing

125

(77.2)

37

(22.8)

25

(67.6)

7

(18.9)

5

(13.5)

HIV Status

Positive

965

(70.6)

402

(29.4)

201

(50.0)

64

(15.9)

137

(34.1)

Negative

12,883

(78.9)

3,454

(21.1)

1,823

(52.8)

866

(25.1)

765

(22.1)

Refused

733

(86.3)

116

(13.7)

73

(62.9)

30

(25.9)

13

(11.2)

Not Offered

1,379

(82.4)

295

(17.6)

168

(56.9)

66

(22.4)

61

(20.7)

Unknown, Missing or Indeterminate

1,699

(78.8)

456

(21.2)

335

(73.5

63

(13.8)

58

(12.7)

Multi-Drug Resistant TB

Yes

251

(82.6)

53

(17.4)

41

(77.4)

12

(22.6)

0

(0.0)

No

16,985

(78.9)

4,552

(21.1)

2,505

(55.0)

1,049

(23.0)

998

(21.9)

Unknown or Missing

423

(78.2)

118

(21.8)

54

(45.7)

28

(23.7)

36

(30.5)

 

1 GENType clusters have two or more cases with matching spoligotype and 24-locus locus mycobacterial interspersed repetitive unit-variable number tandem repeat type within a county during the specified 3-year time period .

2 Alert levels are based on a log-likelihood ratio (LLR), which calculates the geographic concentration of a genotype in a county compared to the rest of the country during a 3-year period.

3 There were 4,723 cases in alerted clusters: 1,034 cases were in 112 (7.3%) High Alert clusters; 1,089 cases were in 361 (23.4%) medium alert clusters and 2,600 were in 1,069 (69.3%) Non-alerted clusters.

Note: Case counts for race categories (American Indian or Alaska Native, Asian, Black or African American, Native Hawaiian or Other Pacific Islander, and White) are mutually exclusive and do not include persons of Hispanic ethnicity or multiple race. Multiple Race does not include persons of Hispanic ethnicity.

See Surveillance Slide #36.

 
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