ORIGINAL RESEARCH
A Cost-Benefit Analysis of Lipid Standardization in the United States

The logic model is a structured flow chart depicting program elements with arrows showing associations and causal pathways. The logic model flows from left to right with columns for inputs, activities, participation, and short-, medium-, and long-term outcomes. Arrows depict relationships between program elements in the same column group or the next group to the right.

Figure 1. Lipid Standardization Program (LSP) and Cholesterol Reference Method Laboratory Network (CRMLN) logic model. Abbreviations: CDC, Centers for Disease Control and Prevention; NHLBI, National Heart, Lung, and Blood Institute; PI, principal investigator; QALY, quality-adjusted life-year.

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% of Benefits Attributable to LSP and CRMLN	Value per Life-Year, $
	50,000	113,000	300,000
0.001	1,000,000	1,526,856	4,053,600
0.010	6,756,000	15,268,560	40,536,000
0.050	33,780,000	76,342,800	202,680,000
0.100	67,560,000	152,685,600	405,360,000
0.500	337,800,000	763,428,000	2,026,800,000
1.000	675,600,000	1,526,856,000	4,053,600,000
2.000	1,351,200,000	3,053,712,000	8,107,200,000
3.000	2,026,800,000	4,580,568,000	12,160,800,000
4.000	2,702,400,000	6,107,424,000	16,214,400,000
5.000	3,378,000,000	7,634,280,000	20,268,000,000

Figure 2. Benefits of life-years gained from the Lipid Standardization Program (LSP) and Cholesterol Reference Method Laboratory Network (CRMLN). Cost of the programs was $1.7 million per year.

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