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Emerging Infectious Diseases Journal
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Volume 8: No. 6, November 2011

ORIGINAL RESEARCH
A Cost-Benefit Analysis of Lipid Standardization in the United States

The logic model is a structured flow chart depicting program elements with arrows showing associations and causal pathways. The logic model flows from left to right with columns for inputs, activities, participation, and short-, medium-, and long-term outcomes. Arrows depict relationships between program elements in the same column group or the next group to the right.

Figure 1. Lipid Standardization Program (LSP) and Cholesterol Reference Method Laboratory Network (CRMLN) logic model. Abbreviations: CDC, Centers for Disease Control and Prevention; NHLBI, National Heart, Lung, and Blood Institute; PI, principal investigator; QALY, quality-adjusted life-year.

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% of Benefits Attributable to LSP and CRMLN Value per Life-Year, $
50,000 113,000 300,000
0.001 1,000,000 1,526,856 4,053,600
0.010 6,756,000 15,268,560 40,536,000
0.050 33,780,000 76,342,800 202,680,000
0.100 67,560,000 152,685,600 405,360,000
0.500 337,800,000 763,428,000 2,026,800,000
1.000 675,600,000 1,526,856,000 4,053,600,000
2.000 1,351,200,000 3,053,712,000 8,107,200,000
3.000 2,026,800,000 4,580,568,000 12,160,800,000
4.000 2,702,400,000 6,107,424,000 16,214,400,000
5.000 3,378,000,000 7,634,280,000 20,268,000,000

Figure 2. Benefits of life-years gained from the Lipid Standardization Program (LSP) and Cholesterol Reference Method Laboratory Network (CRMLN). Cost of the programs was $1.7 million per year.

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The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.


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