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Causal Agent:

Human echinococcosis (hydatidosis, or hydatid disease) is caused by the larval stages of cestodes (tapeworms) of the genus Echinococcus. Echinococcus granulosus causes cystic echinococcosis (CE), the form most frequently encountered; E. multilocularis causes alveolar echinococcosis (AE); E. vogeli causes polycystic echinococcosis; and E. oligarthrus is an extremely rare cause of human echinococcosis.

Life Cycle:

Life cycle of Echinococcus

The adult Echinococcus granulosus (3 to 6 mm long) The number 1 resides in the small bowel of the definitive hosts, dogs or other canids. Gravid proglottids release eggs The number 2 that are passed in the feces. After ingestion by a suitable intermediate host (under natural conditions: sheep, goat, swine, cattle, horses, camel), the egg hatches in the small bowel and releases an oncosphere The number 3 that penetrates the intestinal wall and migrates through the circulatory system into various organs, especially the liver and lungs. In these organs, the oncosphere develops into a cyst The number 4 that enlarges gradually, producing protoscolices and daughter cysts that fill the cyst interior. The definitive host becomes infected by ingesting the cyst-containing organs of the infected intermediate host. After ingestion, the protoscolices The number 5 evaginate, attach to the intestinal mucosa The number 6, and develop into adult stages The number 1 in 32 to 80 days.

The same life cycle occurs with E. multilocularis (1.2 to 3.7 mm), with the following differences: the definitive hosts are foxes, and to a lesser extent dogs, cats, coyotes and wolves; the intermediate host are small rodents; and larval growth (in the liver) remains indefinitely in the proliferative stage, resulting in invasion of the surrounding tissues. With E. vogeli (up to 5.6 mm long), the definitive hosts are bush dogs and dogs; the intermediate hosts are rodents; and the larval stage (in the liver, lungs and other organs) develops both externally and internally, resulting in multiple vesicles. E. oligarthrus (up to 2.9 mm long) has a life cycle that involves wild felids as definitive hosts and rodents as intermediate hosts. Humans become infected by ingesting eggs The number 2, with resulting release of oncospheres The number 3 in the intestine and the development of cysts The number 4, The number 4, The number 4, The number 4, The number 4, The number 4 in various organs.

Life cycle image and information courtesy of DPDx.

 
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  • Page last reviewed: December 12, 2012
  • Page last updated: December 12, 2012
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