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Typhoid Fever (Salmonella typhi)

Contents
Home - National Notifiable Diseases Surveillance System
Overview
Introduction
List of Infectious Nationally Notifiable Condtions
List of Non-Infectious Nationally Notifiable Conditions
Alphabetical List of Case Definitions
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1997 Case Definition

CSTE Position Statement Number: 09-ID-67.

Clinical description

An illness caused by Salmonella typhi that is often characterized by insidious onset of sustained fever, headache, malaise, anorexia, relative bradycardia, constipation or diarrhea, and nonproductive cough. However, many mild and atypical infections occur. Carriage of S. typhi may be prolonged.

Laboratory criteria for diagnosis

  • Isolation of S. typhi from blood, stool, or other clinical specimen

Case classification

Probable: a clinically compatible case that is epidemiologically linked to a confirmed case in an outbreak

Confirmed: a clinically compatible case that is laboratory confirmed

Comment

Isolation of the organism is required for confirmation. Serologic evidence alone is not sufficient for diagnosis. Asymptomatic carriage should not be reported as typhoid fever. Isolates of S. typhi are reported to the Foodborne and Diarrheal Diseases Branch, Division of Bacterial and Mycotic Diseases, National Center for Infectious Diseases, CDC, through the Public Health Laboratory Information System (PHLIS).

The 1997 case definition appearing on this page was originally published in the 1990 MMWR and re-published in the 2009 CSTE position statement 09-ID-67.1,2  Thus, the 1990, 1997, and 2010 versions of the case definition are identical.

References

  1. CDC. (1990). Case Definitions for Public Health Surveillance. MMWR, 39(RR-13), 1-43. http://www.cdc.gov/mmwr/preview/mmwrhtml/00025629.htm
  2. CDC. (1997). Case Definitions for Infectious Conditions Under Public Health Surveillance. MMWR, 46(RR-10), 1-55. http://www.cdc.gov/mmwr/preview/mmwrhtml/00047449.htm

See also

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This page last updated November 17, 2011

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