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Meningococcal Disease (Neisseria meningitidis)
2010 Case Definition
CSTE Position Statement Number: 09-ID-42
Case classification
Suspected:
- Clinical purpura fulminans in the absence of a positive blood culture; or
- Gram-negative diplococci, not yet identified , isolated from a normally sterile body site (e.g., blood or CSF).
Probable:
- detection of N. meningitidis-specific nucleic acid in a specimen obtained from a normally sterile body site (e.g.,. blood or CSF), using a validated polymerase chain reaction (PCR) assay
OR
- detection of N. meningitidis antigen
- in formalin-fixed tissue by immunohistochemistry (IHC); or
- in CSF by latex agglutination.
Confirmed:
- Isolation of Neisseria meningitidis
- from a normally sterile body site (e.g., blood or cerebrospinal fluid, or, less commonly, synovial, pleural, or pericardial fluid), or
- from purpuric lesions.
See also:
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