Haemophilus influenzae, invasive disease

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1997 Case Definition

CSTE Position Statement Number: 09-ID-33

Clinical description

Invasive disease may be manifest as pneumonia, bacteremia, meningitis, epiglottitis, septic arthritis, cellulitis, or purulent pericarditis; less common infections include endocarditis and osteomyelitis.

Case classification

Probable: meningitis with detection of Haemophilus influenzae type b antigen in cerebrospinal fluid (CSF)

Confirmed: isolation of Haemophilus influenzae from a normally sterile body site (e.g., blood or CSF, or, less commonly, joint, pleural, or pericardial fluid)

Comment

Positive antigen test results from urine or serum samples are unreliable for diagnosis of H. influenzae disease.

The 1997 case definition appearing on this page was originally published in the 1990 MMWR and re-published in the 2009 CSTE position statement 09-ID-33.1,2 Thus, the 1990, 1997, and 2010 versions of the case definition are identical.

References

1. CDC. (1990). Case Definitions for Public Health Surveillance. MMWR, 39(RR-13), 1-43. http://www.cdc.gov/mmwr/preview/mmwrhtml/00025629.htm
2. CDC. (1997). Case Definitions for Infectious Conditions Under Public Health Surveillance. MMWR, 46(RR-10), 1-55. http://www.cdc.gov/mmwr/preview/mmwrhtml/00047449.htm

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This page last updated November 17, 2011

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