Disease caused by Streptococcus pneumoniae (pneumococcus) is an important cause of morbidity and mortality in the United States and developing countries. Pneumococcal disease is very prevalent among the very young, the elderly, and immunocompromised persons. This invention includes nucleic acidsa encoding pneumococcal fimbrial protein A suitable for vaccine and diagnostic purposes.

Inventors: Harold Russell, Jacqueline Sampson, and Steven O'Connor

CDC Reference Number: E-157-91/3

USPTO Serial Number: 08/356,106

Patent Number: 6,312,944

License available for diagnostic applications only