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Registries: Immunization Information Systems
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Questions & Answers about
IIS Sentinel Sites
(Q&A) frequently asked questions


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What are IIS Sentinel Sites?
The National Immunization Program (NCIRD) established a group of immunization information systems (IIS) as Sentinel Sites in 2004 from those that receive CDC/NCIRD immunization grant funding. These Sentinel Sites receive additional grant funds to achieve higher standards of data quality and routinely analyze data for programmatic decision-making. These sites partner with NIP in tracking patterns in immunization practices and assessing vaccination coverage of children in specific geographic areas.

Why Sentinel Sites?
Public health officials have the challenging task of determining why children are not fully immunized and studying immunization behavior changes over time. Each working day, tens of thousands of children are immunized at thousands of sites. Parents base immunization decisions on many sources of information. Similarly, providers’ decisions concerning recommendations to administer or withhold immunizations can vary with location and/or time.

Parental acceptance of immunizations can be influenced by the media and other events. To understand changing patterns of acceptance of immunization soon enough to properly respond, the public health community requires an instrument that can monitor the public’s response to events in a timely manner; IIS, within limits, ideally suit this purpose. The National Immunization Survey (NIS), traditionally considered the gold standard of immunization coverage, provides yearly estimates and reflects changes on this time scale. At best, the NIS reflects changes on this time scale. As a result, IIS sentinel sites have been created to respond quickly to changing conditions and populations represented in an IIS are usually well-understood.

No state or local IIS is sufficiently complete yet to support routine assessment of the coverage of an entire population. Analysis of data from a subset of this population in a specific geographic area using Sentinel Sites can provide valuable insights into immunization practices and the factors influencing those practices.

How are Sentinel Sites Selected?
IISs chosen as Sentinel Sites have been state or large urban systems. There are two types of sentinel sites: capacity-building and implementation sites. Capacity-building sites primarily work to meet data quality Registry/IIS Certification Standards and provide support for routine analysis of immunization IIS data. Sites receiving capacity-building funds collect timely and complete immunization histories in a specific geographic area with at least 10,000 children <6 years of age actively participating. Implementation sites accurately assess trends in vaccination coverage for all children in a study population and provide data for public health decision making. Sites receiving implementation funds focus on a larger population (>200,000 children <18 years of age).

Sentinel Sites aim to have the high data quality measures used for IIS certification:

  1. At least 90% of the vaccines administered by providers entered into the IIS’s database within 30 days of vaccine administration.
  2. Have 25% of the National Vaccine Advisory Committee (NVAC) core data elements routinely populated in their database. The aim is to have 50% of the patient data populated with vaccine lot number and vaccine manufacturer.
  3. Have data quality protocols and procedures in place to ensure high levels of accurate and complete vaccination histories with few duplicate records.

What are Sentinel Sites asked to do?
Sentinel Sites report aggregate confidential immunization coverage data to NIP on a quarterly basis. Although data are limited to specific geographic areas, these analyses:

  1. monitor ‘real time’ trends in immunization;
  2. determine how events have impacted immunization acceptance;
  3. answer questions concerning certain vaccines; and
  4. monitor data quality, completeness, and timeliness.

Thus, Sentinel Sites can not only increase their own understanding of the population served but also health care providers’ ability to address changing circumstances within their region. IISs will also have hard data to evaluate their own performance.

Ad-hoc requests occur when NIP determines that events occur which might change immunization acceptance or administration. For example, such requests might follow warnings from professional advisory groups or reports of vaccine shortages. Implementation sites receive ad-hoc requests more frequently and are asked to prepare one journal article for a peer-reviewed scientific journal based on data from their sentinel site population.

Sentinel Sites receive technical consultation from NIP and have access to information obtained from analysis of their own data. Quarterly immunization coverage data are consolidated, de-identified, and returned back to sentinel sites for comparison purposes.

See profiles of current Sentinel Sites.

Who to contact?
For more information on IIS Sentinel Sites, contact Diana Bartlett at zxd5@cdc.gov.

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This page last modified on November 17, 2006
This page last reviewed on November 15, 2006

   

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