Information
on this page was adapted from the Vaccine-Preventable
Disease Surveillance Manual, 3rd Edition,
2002, Chapter 7, Mumps: p.3.
Mumps
Case Definition and Case Classification
The following case definition for
mumps was approved by the Council of
State and Territorial Epidemiologists
(CSTE) in 1999.
Clinical case definition
An
illness with acute onset of unilateral
or bilateral tender, self-limited
swelling of the parotid or other salivary
gland, lasting 2 or more
days, and without other apparent cause.
Laboratory criteria for diagnosis
- Positive
serologic test for mumps immunoglobulin
M (IgM) antibody, or
- Significant
rise between acute- and convalescent-phase
titers in serum mumps immunoglobulin
G (IgG) antibody level by any standard
serologic assay, or
- Isolation
of mumps virus from clinical specimen,
or
- Detection
of viral antigen by reverse transcription
polymerase chain reaction (RT-PCR)
Case classification
Probable: A case that meets the clinical
case definition, has noncontributory
or no serologic or virologic testing,
and is not epidemiologically linked
to a confirmed or probable case.
Confirmed: A case that is laboratory
confirmed or that meets the clinical
case definition and is epidemiologically
linked to a confirmed or probable case.
A laboratory-confirmed case does not
need to meet the clinical case definition.
Comment. False-positive IgM results
by immunofluorescent antibody assays
have been reported.
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