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NIOSH Home > Safety and Health Topics >Skin Exposures and Effects >Occupational & Environmental Exposures of Skin to Chemicals- 2005> Abstracts

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Abstract for Short Course 2.1

 

 

Assessment of dermal exposure

Derk Brouwer
TNO Chemistry, The Netherlands

Improved understanding of the process of dermal exposure has been achieved through a conceptual model, which systematically describes the transport of contaminant mass from exposure sources to the surface of the skin. Recently, CEN (TC 137 WG 6) has proposed a series of definitions on dermal exposure based on the conceptual model of dermal exposure and the official ISEA glossary on exposure terminology. Dermal exposure is defined as process of contact between an agent and human skin at an exposure surface over an exposure period, and may result in mass loading of the exposed skin area.

Measurement methods for dermal exposure assessment can be grouped into three major principles; interception of agent mass transport by the use of collection media placed at the skin surface or replacing work clothing during the sampling time; removal of the agent mass from the skin surface at any given; in situ detection of the agent or a tracer at the skin surface at a given time.

The different sampling and measurement methods based on these principles will be illustrated and discussed in view of the conceptual model, and considerations for sampling strategy.

Content last modified: 14 May 2005

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